HitPredict

Interactor 1: CG12 (P20438)
G1/S-specific cyclin CLN2
Gene: CLN2

Interactor 2: STE20 (Q03497)
Serine/threonine-protein kinase STE20 (EC 2.7.11.1)
Gene: STE20

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.906

Property	Details
Experiments	10359756, 15200949, 24909323, 25619768, 21945277
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cyclin_N~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 545 Sc			1 939
+	Sc
		593370 CG11_YEAST (6-541): 1.12e-151: 447: 56.12		STE20_YEAST (1-939): 0: 786: 100.00
+	Sc
		624716 CG22_YEAST (6-319): 3.55e-71: 237: 14.01		STE20_YEAST (1-939): 0: 786: 100.00
+	Sc
		624662 CG21_YEAST (34-307): 4.92e-58: 202: 11.31		STE20_YEAST (1-939): 0: 786: 100.00
+	Sc
		673217 CGS5_YEAST (36-203): 2.33e-12: 71: 19.41		STE20_YEAST (1-939): 0: 786: 100.00
+	Hs
		538556 CCNB1_HUMAN (2-322): 2.95e-77: 251: 12.81		PKN2_HUMAN (112-933): 4.61e-151: 473: 15.03
+	Hs
		590134 CCNA2_HUMAN (4-302): 3.84e-69: 230: 16.12		AKT2_HUMAN (491-913): 1.21e-145: 442: 21.74
+	Hs
		590133 CCNA2_HUMAN (4-302): 3.84e-69: 230: 16.12		AKT1_HUMAN (515-929): 2.72e-141: 431: 20.51
+	Hs
		590239 CCNA2_HUMAN (4-302): 3.84e-69: 230: 16.12		AKT3_HUMAN (491-913): 2.66e-141: 431: 20.41
+	Hs
		681839 CCNI_HUMAN (55-431): 8.91e-67: 222: 15.89		AKT1_HUMAN (515-929): 2.72e-141: 431: 20.51
+	Hs
		624550 CCNE1_HUMAN (42-391): 4.03e-65: 219: 12.13		AKT1_HUMAN (515-929): 2.72e-141: 431: 20.51
+	Hs
		673024 CCND2_HUMAN (42-318): 1.39e-58: 198: 13.07		AKT1_HUMAN (515-929): 2.72e-141: 431: 20.51