HitPredict

Interactor 1: KCNA4 (P22459)
Potassium voltage-gated channel subfamily A member 4 (HPCN2) (Voltage-gated K(+) channel HuKII) (Voltage-gated potassium channel HBK4) (Voltage-gated potassium channel HK1) (Voltage-gated potassium channel subunit Kv1.4)
Gene: KCNA4

Interactor 2: SNTB1 (Q13884)
Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)
Gene: SNTB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Hs			1 538
+	Hs
		608228 KCNA4_HUMAN (1-653): 0: 595: 100.00		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		608227 KCNA4_HUMAN (1-653): 0: 595: 100.00		SNTA1_HUMAN (15-538): 8.44e-135: 402: 47.83
+	Hs
		608274 KCNA5_HUMAN (50-636): 1.02e-149: 448: 54.82		SNTA1_HUMAN (15-538): 8.44e-135: 402: 47.83
+	Hs
		159156 KCNA4_HUMAN (1-653): 0: 595: 100.00		CSKP_HUMAN (28-512): 1.27e-73: 253: 10.90
+	Hs
		608231 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG2_HUMAN (29-446): 8.3e-26: 114: 12.82
+	Hs
		608221 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG4_HUMAN (62-203): 1.16e-23: 107: 28.57
+	Hs
		608224 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Rn
		548174 KCNA4_RAT (1-653): 0: 587: 96.03		DLG4_RAT (62-203): 1.07e-23: 107: 28.57
+	Hs
		608244 KCNA4_HUMAN (1-653): 0: 595: 100.00		DLG3_HUMAN (39-380): 6.2e-19: 92.7: 14.80
+	Mm
		1142574 KCNA4_MOUSE (1-653): 0: 576: 96.79		DLG4_MOUSE (62-203): 1.24e-23: 107: 27.89
+	Rn
		548175 KCNA4_RAT (1-653): 0: 587: 96.03		DLG3_RAT (1-380): 5.11e-19: 93.1: 13.94
+	Rn
		580271 KCNA5_RAT (44-636): 7.42e-156: 464: 55.28		DLG1_RAT (7-321): 5.68e-22: 102: 15.66
+	Hs
		602901 KCNA3_HUMAN (84-653): 3.65e-154: 459: 60.07		DLG4_HUMAN (62-203): 1.16e-23: 107: 28.57
+	Hs
		602905 KCNA3_HUMAN (84-653): 3.65e-154: 459: 60.07		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		608268 KCNA5_HUMAN (50-636): 1.02e-149: 448: 54.82		DLG4_HUMAN (62-203): 1.16e-23: 107: 28.57
+	Mm
		927733 KCNA2_MOUSE (140-653): 1.88e-150: 446: 65.95		DLG4_MOUSE (62-203): 1.24e-23: 107: 27.89
+	Hs
		942333 KCNA1_HUMAN (140-653): 2.24e-150: 446: 65.56		DLG4_HUMAN (62-203): 1.16e-23: 107: 28.57
+	Hs
		558713 KCNA2_HUMAN (140-653): 4.02e-150: 445: 65.76		DLG4_HUMAN (62-203): 1.16e-23: 107: 28.57
+	Mm
		558703 KCNA1_MOUSE (140-653): 8.02e-150: 444: 65.56		DLG4_MOUSE (62-203): 1.24e-23: 107: 27.89
+	Hs
		608272 KCNA5_HUMAN (50-636): 1.02e-149: 448: 54.82		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33