HitPredict

Interactor 1: RCCD1 (A6NED2)
RCC1 domain-containing protein 1
Gene: RCCD1

Interactor 2: HERC4 (Q5GLZ8)
Probable E3 ubiquitin-protein ligase HERC4 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 4) (HECT-type E3 ubiquitin transferase HERC4)
Gene: HERC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 1057
+	Hs
		1204524 HERC4_HUMAN (1-301): 1.66e-65: 226: 18.71		HERC4_HUMAN (1-1057): 0: 1109: 100.00
+	Hs
		1138972 HERC6_HUMAN (1-237): 4.02e-51: 185: 20.75		HERC3_HUMAN (1-1056): 0: 992: 55.91
+	Hs
		1138974 RCBT1_HUMAN (1-189): 1.56e-31: 126: 15.98		HERC3_HUMAN (1-1056): 0: 992: 55.91
+	Hs
		64863 RCCD1_HUMAN (1-376): 1.19e-100: 304: 100.00		UBE3A_HUMAN (431-1057): 1.04e-170: 525: 29.18
+	Hs
		132354 RCC2_HUMAN (35-376): 1.44e-53: 186: 17.59		WWP2_HUMAN (375-1055): 0: 608: 20.69
+	Hs
		1430227 HERC5_HUMAN (1-205): 1e-21: 99.1: 19.71		WWP1_HUMAN (413-1055): 0: 625: 20.78
+	Hs
		1437707 HERC5_HUMAN (1-205): 1e-21: 99.1: 19.71		SMUF2_HUMAN (503-1054): 0: 567: 21.14
+	Hs
		342840 HERC2_HUMAN (178-371): 1.85e-29: 122: 24.27		UBE3A_HUMAN (431-1057): 1.04e-170: 525: 29.18
+	Mm
		148242 HERC2_MOUSE (178-371): 3.09e-29: 121: 24.76		UBE3A_MOUSE (395-1057): 5.36e-171: 525: 28.83
+	Hs
		1260714 HERC5_HUMAN (1-205): 1e-21: 99.1: 19.71		HECW1_HUMAN (379-1056): 5.98e-168: 537: 20.99
+	Hs
		1050567 HERC5_HUMAN (1-205): 1e-21: 99.1: 19.71		UBE3A_HUMAN (431-1057): 1.04e-170: 525: 29.18
+	At
		1426712 UVR8_ARATH (1-298): 5.31e-72: 233: 19.37		UVR8_ARATH (4-315): 1.21e-43: 166: 32.70
+	Hs
		1204533 HERC4_HUMAN (1-301): 1.66e-65: 226: 18.71		HERC6_HUMAN (1-207): 8.11e-38: 156: 27.11
+	Hs
		1309275 HERC6_HUMAN (1-237): 4.02e-51: 185: 20.75		HERC6_HUMAN (1-207): 8.11e-38: 156: 27.11
+	Hs
		342876 HERC3_HUMAN (1-233): 1.25e-47: 175: 15.08		HERC2_HUMAN (4-157): 1.71e-12: 74.3: 30.63
+	Hs
		342886 HERC1_HUMAN (1-184): 9.53e-35: 138: 19.47		HERC2_HUMAN (4-157): 1.71e-12: 74.3: 30.63
+	Hs
		342707 HERC2_HUMAN (178-371): 1.85e-29: 122: 24.27		HERC2_HUMAN (4-157): 1.71e-12: 74.3: 30.63