HitPredict

Interactor 1: KAPCG (P22612)
cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11)
Gene: PRKACG

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 2346
+	Hs
		605714 KAPCA_HUMAN (1-351): 5.8e-162: 458: 82.91		MYOME_HUMAN (1-2346): 0: 679: 100.00
+	Hs
		651670 KAPCB_HUMAN (1-351): 1.92e-160: 454: 78.63		MYOME_HUMAN (1-2346): 0: 679: 100.00
+	Mm
		996601 KAPCB_MOUSE (1-351): 4.53e-159: 451: 78.06		MYOME_MOUSE (1-2346): 1.06e-159: 550: 66.87
+	Hs
		651734 KAPCB_HUMAN (1-351): 1.92e-160: 454: 78.63		MYH2_HUMAN (1265-2339): 8.32e-34: 145: 10.08
+	Hs
		556840 KAPCB_HUMAN (1-351): 1.92e-160: 454: 78.63		MYH1_HUMAN (1279-2339): 1.56e-31: 138: 9.76
+	Hs
		651743 KAPCB_HUMAN (1-351): 1.92e-160: 454: 78.63		MYH4_HUMAN (1265-2339): 3.03e-31: 137: 10.00
+	Hs
		562995 KAPCB_HUMAN (1-351): 1.92e-160: 454: 78.63		MYH6_HUMAN (1279-2312): 4.48e-30: 133: 9.72
+	Hs
		605578 KAPCA_HUMAN (1-351): 5.8e-162: 458: 82.91		MYH10_HUMAN (1785-2317): 1.38e-14: 82.8: 10.17
+	Hs
		122910 SGK1_HUMAN (7-340): 4.44e-138: 400: 39.53		MYH1_HUMAN (1279-2339): 1.56e-31: 138: 9.76
+	Hs
		605577 KAPCA_HUMAN (1-351): 5.8e-162: 458: 82.91		MYH9_HUMAN (1788-2316): 5.15e-13: 77.4: 12.36
+	Hs
		605788 KAPCA_HUMAN (1-351): 5.8e-162: 458: 82.91		CK5P2_HUMAN (434-1035): 2.54e-11: 71.9: 10.82
+	Hs
		651708 KAPCB_HUMAN (1-351): 1.92e-160: 454: 78.63		CK5P2_HUMAN (434-1035): 2.54e-11: 71.9: 10.82
+	Mm
		591067 KPCE_MOUSE (4-351): 1.24e-138: 412: 34.63		MYH7_MOUSE (672-1581): 3.2e-21: 104: 13.84
+	Hs
		728066 AKT1_HUMAN (7-347): 4.62e-147: 425: 38.51		MYH9_HUMAN (1788-2316): 5.15e-13: 77.4: 12.36
+	Hs
		587568 AKT1_HUMAN (7-347): 4.62e-147: 425: 38.51		DESP_HUMAN (6-681): 6.11e-10: 67.4: 20.72
+	Hs
		772751 KPCE_HUMAN (4-351): 5.52e-139: 413: 34.07		MYH9_HUMAN (1788-2316): 5.15e-13: 77.4: 12.36
+	Mm
		591040 KPCE_MOUSE (4-351): 1.24e-138: 412: 34.63		MYH6_MOUSE (1302-2008): 2.49e-11: 71.9: 10.14
+	Hs
		587626 KPCE_HUMAN (4-351): 5.52e-139: 413: 34.07		DESP_HUMAN (6-681): 6.11e-10: 67.4: 20.72