HitPredict

Interactor 1: FBLN1 (P23142)
Fibulin-1 (FIBL-1)
Gene: FBLN1

Interactor 2: EGFL7 (Q9UHF1)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	EGF_CA~FXa_inhibition
Common GO terms	GO:0005509 - calcium ion binding GO:0005576 - extracellular region
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 703 Hs			1 273
+	Hs
		654552 FBLN1_HUMAN (1-703): 5.06e-90: 297: 100.00		EGFL8_HUMAN (14-273): 5.92e-38: 136: 34.44
+	Hs
		654544 FBLN1_HUMAN (1-703): 5.06e-90: 297: 100.00		NELL1_HUMAN (82-180): 4.1e-26: 109: 36.63
+	Hs
		572680 FBLN1_HUMAN (1-703): 5.06e-90: 297: 100.00		NID1_HUMAN (60-271): 1.89e-16: 81: 16.46
+	Mm
		1032094 NOTC1_MOUSE (9-644): 6.29e-42: 167: 14.42		EGFL7_MOUSE (1-272): 1.08e-38: 138: 78.10
+	Hs
		857580 NOTC1_HUMAN (5-628): 5.69e-37: 151: 12.37		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Hs
		1366681 SORL_HUMAN (23-383): 6.6e-29: 126: 11.72		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Hs
		1324544 LTBP4_HUMAN (23-460): 1.23e-22: 106: 17.27		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Hs
		1086457 FBLN3_HUMAN (63-309): 9.5e-21: 98.1: 22.13		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Mm
		1223430 NOTC3_MOUSE (6-463): 7.62e-22: 103: 12.39		EGFL7_MOUSE (1-272): 1.08e-38: 138: 78.10
+	Hs
		133041 MATN2_HUMAN (3-364): 2.6e-25: 114: 18.28		NELL1_HUMAN (82-180): 4.1e-26: 109: 36.63
+	Hs
		133045 MATN2_HUMAN (3-364): 2.6e-25: 114: 18.28		NELL2_HUMAN (82-176): 7.62e-26: 108: 34.65
+	Hs
		666725 TENA_HUMAN (290-657): 9.93e-28: 122: 13.16		NID2_HUMAN (5-272): 9.09e-22: 96.8: 11.42
+	Hs
		857407 JAG1_HUMAN (75-660): 5.12e-39: 157: 14.74		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57
+	Hs
		1324525 LTBP4_HUMAN (23-460): 1.23e-22: 106: 17.27		NELL1_HUMAN (82-180): 4.1e-26: 109: 36.63
+	Hs
		1324535 LTBP4_HUMAN (23-460): 1.23e-22: 106: 17.27		NELL2_HUMAN (82-176): 7.62e-26: 108: 34.65
+	Hs
		133024 MATN2_HUMAN (3-364): 2.6e-25: 114: 18.28		NID2_HUMAN (5-272): 9.09e-22: 96.8: 11.42
+	Hs
		857370 NOTC1_HUMAN (5-628): 5.69e-37: 151: 12.37		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57
+	Hs
		317563 NOTC2_HUMAN (22-463): 3.59e-19: 95: 11.75		SLIT2_HUMAN (59-271): 1.73e-25: 107: 12.29
+	Hs
		1308072 SORL_HUMAN (23-383): 6.6e-29: 126: 11.72		EGFL6_HUMAN (22-256): 1.21e-13: 72.5: 16.34