HitPredict

Interactor 1: FBLN1 (P23142)
Fibulin-1 (FIBL-1)
Gene: FBLN1

Interactor 2: EGFL8 (Q99944)
Epidermal growth factor-like protein 8 (EGF-like protein 8) (Vascular endothelial statin-2) (VE-statin-2)
Gene: EGFL8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	EGF~EGF_CA, EGF_CA~EGF_CA
Common GO terms	GO:0005509 - calcium ion binding GO:0005576 - extracellular region
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 703 Hs			1 293
+	Hs
		654564 FBLN1_HUMAN (1-703): 5.06e-90: 297: 100.00		EGFL7_HUMAN (16-285): 4.49e-46: 158: 33.82
+	Hs
		654544 FBLN1_HUMAN (1-703): 5.06e-90: 297: 100.00		NELL1_HUMAN (88-186): 3.46e-23: 101: 31.43
+	Hs
		654492 FBLN1_HUMAN (1-703): 5.06e-90: 297: 100.00		NOTC2_HUMAN (6-210): 1.58e-10: 64: 10.66
+	Mm
		1032094 NOTC1_MOUSE (9-644): 6.29e-42: 167: 14.42		EGFL7_MOUSE (18-284): 2.75e-44: 153: 33.09
+	Hs
		857580 NOTC1_HUMAN (5-628): 5.69e-37: 151: 12.37		EGFL7_HUMAN (16-285): 4.49e-46: 158: 33.82
+	Hs
		1366681 SORL_HUMAN (23-383): 6.6e-29: 126: 11.72		EGFL7_HUMAN (16-285): 4.49e-46: 158: 33.82
+	Mm
		1032083 NOTC1_MOUSE (9-644): 6.29e-42: 167: 14.42		DLL1_MOUSE (6-152): 1.69e-11: 66.3: 20.00
+	Hs
		1008015 JAG1_HUMAN (75-660): 5.12e-39: 157: 14.74		NOTC2_HUMAN (6-210): 1.58e-10: 64: 10.66
+	Hs
		857407 JAG1_HUMAN (75-660): 5.12e-39: 157: 14.74		NOTC1_HUMAN (95-173): 8.95e-09: 58.6: 27.71
+	Hs
		133041 MATN2_HUMAN (3-364): 2.6e-25: 114: 18.28		NELL1_HUMAN (88-186): 3.46e-23: 101: 31.43
+	Hs
		857423 NOTC1_HUMAN (5-628): 5.69e-37: 151: 12.37		NOTC2_HUMAN (6-210): 1.58e-10: 64: 10.66
+	Hs
		857370 NOTC1_HUMAN (5-628): 5.69e-37: 151: 12.37		NOTC1_HUMAN (95-173): 8.95e-09: 58.6: 27.71
+	Hs
		1324525 LTBP4_HUMAN (23-460): 1.23e-22: 106: 17.27		NELL1_HUMAN (88-186): 3.46e-23: 101: 31.43
+	Hs
		133045 MATN2_HUMAN (3-364): 2.6e-25: 114: 18.28		NELL2_HUMAN (95-186): 3.22e-19: 89.4: 29.59
+	Hs
		1308072 SORL_HUMAN (23-383): 6.6e-29: 126: 11.72		EGFL6_HUMAN (34-227): 4.12e-13: 71.4: 17.24
+	Hs
		132999 MATN2_HUMAN (3-364): 2.6e-25: 114: 18.28		FBN2_HUMAN (111-185): 4.67e-09: 59.4: 32.10
+	Hs
		1047630 LTBP4_HUMAN (23-460): 1.23e-22: 106: 17.27		NOTC2_HUMAN (6-210): 1.58e-10: 64: 10.66
+	Hs
		351510 FBLN4_HUMAN (77-382): 9.67e-24: 106: 26.62		FBN1_HUMAN (111-185): 6.12e-09: 59: 30.86
+	Hs
		772288 LTBP4_HUMAN (23-460): 1.23e-22: 106: 17.27		FBN1_HUMAN (111-185): 6.12e-09: 59: 30.86