HitPredict

Interactor 1: TF3B (P29056)
Transcription factor IIIB 70 kDa subunit (TFIIIB) (B-related factor 1) (BRF-1)
Gene: BRF1

Interactor 2: TFC5 (P46678)
Transcription factor TFIIIB component B'' (TFIIIB90)
Gene: BDP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.966

The method score is based on:

Property	Details
Experiments	7568218, 24277937, 8662956, 26055328, 16551611, 19086269, 30593915, 37968396
Identification Methods	comigration in non denaturing gel electrophoresis, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	BRF1~Myb_DNA-bind_7, Myb_DNA-bind_7~TFIIB
Common GO terms	GO:0000126 - transcription factor TFIIIB complex GO:0000995 - RNA polymerase III general transcription initiation factor activity GO:0001112 - DNA-templated transcription open complex formation GO:0001156 - TFIIIC-class transcription factor complex binding GO:0005654 - nucleoplasm and 2 others more... GO:0006359 - regulation of transcription by RNA polymerase III GO:0070898 - RNA polymerase III preinitiation complex assembly
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	596
Sc

1	594

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024