HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	33961781, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1164
+	Hs
		971839 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		TSC1_HUMAN (1-1164): 0: 749: 100.00
+	Mm
		972314 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		TSC1_MOUSE (1-1164): 0: 711: 86.98
+	Mm
		990054 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		TSC1_MOUSE (1-1164): 0: 711: 86.98
+	Hs
		971518 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		DCTN1_HUMAN (540-1022): 7.73e-59: 224: 16.33
+	Hs
		971722 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		PHLB1_HUMAN (337-1109): 3.62e-29: 128: 14.84
+	Mm
		990028 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		MYH9_MOUSE (536-1164): 2.34e-30: 133: 9.76
+	Hs
		776794 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MYH11_HUMAN (363-1048): 6.49e-27: 121: 9.94
+	Hs
		971744 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		RB6I2_HUMAN (349-1108): 9.63e-26: 117: 9.33
+	Hs
		690788 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MYH11_HUMAN (363-1048): 6.49e-27: 121: 9.94
+	Mm
		990059 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		MY18A_MOUSE (359-1062): 1.24e-26: 120: 9.86
+	Hs
		773148 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MYH10_HUMAN (360-988): 3.47e-23: 109: 10.20
+	Hs
		971623 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MRCKA_HUMAN (485-981): 2.61e-22: 106: 10.90
+	Hs
		971450 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		CGNL1_HUMAN (721-1163): 1.41e-20: 100: 10.69
+	Hs
		556897 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MYH7_HUMAN (394-967): 1.34e-22: 107: 11.07
+	Mm
		989976 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		MYH10_MOUSE (686-1157): 6.38e-19: 95.6: 11.52
+	Mm
		98050 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		DESP_MOUSE (718-1163): 2.32e-13: 77.2: 10.81
+	Hs
		971606 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		CYTSB_HUMAN (740-1117): 1.38e-12: 74.5: 12.41
+	Hs
		971486 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		ROCK1_HUMAN (412-900): 4.06e-10: 66.4: 9.64
+	Dm
		1019899 1433E_DROME (2-242): 6.8e-143: 401: 65.02		Q9VCC9_DROME (782-1098): 8.41e-11: 68.7: 10.00
+	Hs
		690784 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MYH9_HUMAN (880-1164): 1.19e-09: 65.2: 7.99