HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: ULK4 (Q96C45)
Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4)
Gene: ULK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1275
+	Xl
		237423 O57468_XENLA (2-243): 4.55e-144: 404: 64.75		Q804T2_XENLA (3-703): 4.92e-171: 526: 16.09
+	Mm
		972209 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		MARK2_MOUSE (3-703): 3.88e-166: 515: 15.03
+	Hs
		692031 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MARK3_HUMAN (3-703): 5.72e-166: 514: 15.05
+	Hs
		971697 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MARK2_HUMAN (3-703): 4.2e-164: 511: 15.03
+	Mm
		972206 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		MARK3_MOUSE (3-703): 7.53e-165: 511: 14.67
+	Xl
		237424 O57468_XENLA (2-243): 4.55e-144: 404: 64.75		Q8QGV3_XENLA (3-703): 2.38e-158: 495: 15.35
+	Hs
		972078 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MARK1_HUMAN (3-703): 1.41e-153: 483: 14.34
+	Mm
		972294 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		MARK1_MOUSE (3-703): 3.05e-151: 477: 14.34
+	Hs
		971486 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		ROCK1_HUMAN (2-754): 3.36e-132: 441: 15.22
+	Hs
		971885 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MARK4_HUMAN (3-704): 3.05e-134: 430: 14.31
+	Mm
		972284 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		MARK4_MOUSE (3-704): 2.95e-134: 430: 14.04
+	Hs
		244241 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		NUAK1_HUMAN (3-635): 9.21e-126: 405: 15.43
+	Mm
		972241 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		NUAK1_MOUSE (3-635): 4.58e-126: 405: 15.74
+	Hs
		728147 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		AKT1_HUMAN (1-349): 7.81e-123: 390: 21.33
+	Hs
		971658 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		ULK3_HUMAN (1-279): 2.63e-32: 134: 32.88
+	Hs
		212649 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		DAPK3_HUMAN (2-283): 1.1e-26: 117: 30.07
+	Hs
		972086 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		PAK5_HUMAN (1-283): 5.33e-26: 117: 32.17
+	Hs
		354631 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		PAK4_HUMAN (1-283): 4.99e-25: 113: 29.37
+	Hs
		972035 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		PAK6_HUMAN (7-279): 7.04e-25: 113: 29.35
+	Hs
		279142 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		ULK1_HUMAN (10-247): 4.72e-24: 112: 28.63