HitPredict

Interactor 1: RASK (P32883)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: Kras

Interactor 2: Q9JJU6 (Q9JJU6)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: Braf

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, RBD~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Mm			1 373
+	Hs
		349101 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		BRAF_HUMAN (1-373): 0: 567: 94.39
+	Hs
		348493 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		BRAF_HUMAN (1-373): 0: 567: 94.39
+	Hs
		349847 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		BRAF_HUMAN (1-373): 0: 567: 94.39
+	Mm
		655955 RASH_MOUSE (1-188): 3.11e-87: 256: 86.77		BRAF_MOUSE (1-356): 0: 533: 90.73
+	Rn
		507685 RASH_RAT (1-188): 3.11e-87: 256: 86.77		RAF1_RAT (40-372): 4.83e-136: 404: 37.36
+	Hs
		349052 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		RAF1_HUMAN (40-372): 1.17e-135: 403: 37.07
+	Mm
		1142565 RASH_MOUSE (1-188): 3.11e-87: 256: 86.77		RAF1_MOUSE (40-372): 2.37e-135: 402: 37.07
+	Hs
		348461 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		RAF1_HUMAN (40-372): 1.17e-135: 403: 37.07
+	Rn
		442943 RASK_RAT (1-189): 2.66e-78: 233: 100.00		RAF1_RAT (40-372): 4.83e-136: 404: 37.36
+	Hs
		349785 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		RAF1_HUMAN (40-372): 1.17e-135: 403: 37.07
+	Mm
		699624 RASK_MOUSE (1-189): 2.66e-78: 233: 100.00		RAF1_MOUSE (40-372): 2.37e-135: 402: 37.07
+	Rn
		534421 RASH_RAT (1-188): 3.11e-87: 256: 86.77		ARAF_RAT (75-371): 6.74e-125: 374: 41.25
+	Hs
		349082 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		ARAF_HUMAN (75-371): 9.88e-125: 373: 42.95
+	Hs
		348480 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		ARAF_HUMAN (75-371): 9.88e-125: 373: 42.95
+	Mm
		384063 RASH_MOUSE (1-188): 3.11e-87: 256: 86.77		ARAF_MOUSE (75-371): 1.28e-123: 370: 41.25
+	Hs
		348865 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		Q96II5_HUMAN (75-371): 3.28e-123: 369: 42.62
+	Hs
		349820 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		ARAF_HUMAN (75-371): 9.88e-125: 373: 42.95
+	Mm
		384059 RASK_MOUSE (1-189): 2.66e-78: 233: 100.00		ARAF_MOUSE (75-371): 1.28e-123: 370: 41.25
+	Dm
		442988 RAS1_DROME (1-165): 2.98e-88: 258: 86.06		KRAF1_DROME (1-371): 1.86e-109: 338: 30.18
+	Ce
		612364 LET60_CAEEL (1-189): 5.1e-86: 252: 75.13		KRAF1_CAEEL (79-330): 1.27e-81: 267: 31.27