Protein: PK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)

Gene: PK3CD, PIK3CD
Organism: Homo sapiens
Interactions: 23
UniProt ID: O00329

Gene Ontology (top 5):
GO:0001779 - natural killer cell differentiation
GO:0001819 - positive regulation of cytokine production
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002250 - adaptive immune response
GO:0002551 - mast cell chemotaxis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

132787

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

11

20

Small-scale

0.980

High

132797

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

5

20

High-throughput

0.924

High

132783

RASH
GTPase HRas

3

20

Small-scale

0.822

High

132781

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

2

20

Small-scale

0.806

High

132790

PK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

1

11

Small-scale

0.724

High

132786

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.618

High

132789

CRK
Adapter molecule crk

1

18

High-throughput

0.618

High

132791

RACK1
Small ribosomal subunit protein RACK1

1

6

Small-scale

0.618

High

132780

PK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

1

13

Small-scale

0.575

High

132795

A16L1
Autophagy-related protein 16-1

1

9

High-throughput

0.575

High

132792

TAGL
Transgelin

1

2

Small-scale

0.561

High

132785

CD37
Leukocyte antigen CD37

1

3

Small-scale

0.479

High

132794

TNIP1
TNFAIP3-interacting protein 1

1

11

Small-scale

0.479

High

132800

ZDH18
Palmitoyltransferase ZDHHC18

1

5

Small-scale

0.479

High

132788

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

132793

DDR1
Epithelial discoidin domain-containing receptor 1

1

20

Small-scale

0.445

High

132782

TNPO2
Transportin-2

1

0

High-throughput

0.438

High

132798

MCRI2
MAPK regulated corepressor interacting protein 2

1

0

High-throughput

0.438

High

132796

ZDH23
Palmitoyltransferase ZDHHC23

1

8

Small-scale

0.437

High

132801

RALY
RNA-binding protein Raly

1

2

High-throughput

0.417

High

132799

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.282

High

132784

OSTP
Osteopontin

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025