Interactor 1: MCM5 (P29496)
Minichromosome maintenance protein 5 (EC 3.6.4.12) (Cell division control protein 46)
Gene: MCM5

Interactor 2: SLD5 (Q03406)
DNA replication complex GINS protein SLD5
Gene: SLD5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 25313033, 21362622, 21868389, 25342810, 23499444, 26255844, 16531994, 28355556, 30104407, 32804080, 32075754, 34700328, 37968396, 39039287, 22325992, 22433841, 16429126
Identification Methods biochemical, pull down, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM_N~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0031261 - DNA replication preinitiation complex
GO:0043596 - nuclear replication fork
GO:0071162 - CMG complex
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 775
Sc

1 294
+ Sc
+ Sc
+ Hs
+ Dm
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Sc
+ Dm

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Last updated: 11Aug2025