Protein: SLD5
DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]

Gene: SLD5, GINS4
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q9BRT9

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0000811 - GINS complex
GO:0001833 - inner cell mass cell proliferation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1411875

PSF2
DNA replication complex GINS protein PSF2

8

6

Small-scale

0.972

High

1411865

PSF3
DNA replication complex GINS protein PSF3

6

4

Small-scale

0.946

High

281243

CDC45
Cell division control protein 45 homolog

5

3

Small-scale

0.920

High

1130907

PSF1
DNA replication complex GINS protein PSF1

5

4

Small-scale

0.918

High

888289

MCM2
DNA replication licensing factor MCM2

5

16

Small-scale

0.918

High

756323

MCM7
DNA replication licensing factor MCM7

4

15

Small-scale

0.895

High

943658

SIK1
Serine/threonine-protein kinase SIK1

6

0

Small-scale

0.708

High

1411867

TIPIN
TIMELESS-interacting protein

3

2

High-throughput

0.667

High

591818

H2AX
Histone H2AX

2

1

High-throughput

0.628

High

1399144

TOX2
TOX high mobility group box family member 2

2

1

High-throughput

0.628

High

669989

MCM3
DNA replication licensing factor MCM3

1

17

Small-scale

0.618

High

755777

MCM4
DNA replication licensing factor MCM4

1

13

Small-scale

0.618

High

756035

MCM5
DNA replication licensing factor MCM5

1

15

Small-scale

0.618

High

1128268

MCM6
DNA replication licensing factor MCM6

1

17

Small-scale

0.618

High

696353

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

1

Small-scale

0.611

High

1411872

CNBP1
Beta-catenin-interacting protein 1

2

1

High-throughput

0.606

High

1006943

KC1G2
Casein kinase I isoform gamma-2

2

0

High-throughput

0.602

High

1229370

LHX8
LIM/homeobox protein Lhx8

2

0

High-throughput

0.580

High

1396250

ASPP1
Apoptosis-stimulating of p53 protein 1

2

0

High-throughput

0.580

High

1396895

KI16B
Kinesin-like protein KIF16B

2

0

High-throughput

0.580

High

1411868

PBX4
Pre-B-cell leukemia transcription factor 4

2

0

High-throughput

0.580

High

1411870

DMAP1
DNA methyltransferase 1-associated protein 1

2

0

High-throughput

0.580

High

1411871

BIN3
Bridging integrator 3

2

0

High-throughput

0.580

High

315951

RECQ4
ATP-dependent DNA helicase Q4

2

0

Small-scale

0.559

High

1411866

MCMBP
Mini-chromosome maintenance complex-binding protein

2

0

Small-scale

0.559

High

254417

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.536

High

1065396

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

1372466

TP4A1
Protein tyrosine phosphatase type IVA 1

1

1

High-throughput

0.536

High

589547

RFA2
Replication protein A 32 kDa subunit

1

0

Small-scale

0.513

High

709004

T2EB
Transcription initiation factor IIE subunit beta

1

0

High-throughput

0.513

High

769027

RFA3
Replication protein A 14 kDa subunit

1

0

Small-scale

0.513

High

1017168

H33
Histone H3.3

1

0

High-throughput

0.513

High

1411869

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.513

High

488024

DPOLA
DNA polymerase alpha catalytic subunit

1

7

Small-scale

0.501

High

703043

DPOD1
DNA polymerase delta catalytic subunit

1

7

Small-scale

0.501

High

1060481

DPOE1
DNA polymerase epsilon catalytic subunit A

1

7

Small-scale

0.501

High

1362061

LZIC
Protein LZIC

1

1

High-throughput

0.489

High

419174

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.479

High

260379

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

762044

GRK5
G protein-coupled receptor kinase 5

1

0

High-throughput

0.458

High

828921

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

942849

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

1255285

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1411873

DONS
Protein downstream neighbor of Son

1

0

Small-scale

0.458

High

1411874

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.458

High

330294

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.426

High

1249540

AMTN
Amelotin

1

0

High-throughput

0.279

Low

1331426

MB213
Protein mab-21-like 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025