HitPredict

Interactor 1: H4 (P62799)
Histone H4
Gene: H4

Interactor 2: Q92133 (Q92133)
Histone H3
Gene: h3c8.S

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	23178455, 23698368
Identification Methods	pull down, molecular sieving
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CENP-T_C~Histone
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 103 Xl			1 136
+	Hs
		917093 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H31_HUMAN (1-136): 9.92e-63: 189: 98.53
+	Mm
		918236 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		H31_MOUSE (1-136): 9.92e-63: 189: 98.53
+	Hs
		917112 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H33_HUMAN (1-136): 6.98e-62: 187: 96.32
+	Hs
		917352 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H31T_HUMAN (1-136): 9.38e-62: 187: 96.32
+	Mm
		918240 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		H33_MOUSE (1-136): 6.98e-62: 187: 96.32
+	Ce
		445733 H4_CAEEL (1-103): 1.41e-48: 151: 99.03		H3_CAEEL (1-136): 3.24e-61: 186: 96.32
+	Xl
		917054 H4_XENLA (1-103): 1.38e-48: 151: 100.00		H32_XENLA (1-136): 1.59e-61: 186: 99.27
+	Hs
		917483 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H32_HUMAN (1-136): 1.59e-61: 186: 99.27
+	Mm
		918239 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		H32_MOUSE (1-136): 1.59e-61: 186: 99.27
+	Hs
		917448 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H3C_HUMAN (1-136): 3.72e-59: 180: 93.38
+	Sp
		448920 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		H31_SCHPO (1-136): 1.07e-59: 182: 91.18
+	Hs
		1174638 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		H32_HUMAN (1-136): 1.59e-61: 186: 99.27
+	Sc
		356652 H4_YEAST (18-103): 6.13e-41: 132: 90.70		H3_YEAST (1-136): 3.69e-56: 173: 88.24
+	Ce
		711990 H4_CAEEL (1-103): 1.41e-48: 151: 99.03		HCP3L_CAEEL (11-131): 4.6e-44: 146: 45.16
+	Hs
		828186 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CENPA_HUMAN (9-133): 8.1e-45: 144: 50.00
+	Kl
		1150023 Q6CMU6_KLULA (18-103): 9.41e-42: 134: 91.86		CENPA_KLULA (14-134): 9.56e-44: 143: 54.03
+	Sc
		356401 H4_YEAST (18-103): 6.13e-41: 132: 90.70		CENPA_YEAST (18-134): 1.35e-41: 139: 55.83