Interactor 1: AGTR1 (P30556)
Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1 receptor)
Gene: AGTR1
Interactor 2: GNA12 (Q03113)
Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)
Gene: GNA12
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28298427 |
| Identification Methods | two hybrid, ubiquitin reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~G-alpha |
| Common GO terms | GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway GO:0007266 - Rho protein signal transduction |
| Homologous interactions | 12 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
