HitPredict

Interactor 1: B3KQF8 (B3KQF8)
cDNA FLJ90387 fis, clone NT2RP2005391, highly similar to Homo sapiens activating transcription factor 7 interacting protein (ATF7IP), mRNA
Gene: B3KQF8

Interactor 2: SRBP2 (Q12772)
Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2 (Transcription factor SREBF2)]
Gene: SREBF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	20936779
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 881 Hs			1 1141
+	Hs
		1016080 MCAF1_HUMAN (1-881): 5.92e-124: 406: 99.55		SRBP2_HUMAN (1-1141): 0: 1168: 100.00
+	Hs
		1167113 MCAF1_HUMAN (1-881): 5.92e-124: 406: 99.55		CBP_HUMAN (5-492): 1.07e-29: 130: 12.88
+	Hs
		1137448 MCAF2_HUMAN (563-871): 4.55e-28: 123: 23.63		MCAF1_HUMAN (17-480): 6.91e-28: 124: 12.42
+	Hs
		1170076 SRCAP_HUMAN (92-880): 3.35e-22: 105: 12.04		CBP_HUMAN (5-492): 1.07e-29: 130: 12.88
+	Hs
		554303 MUC1_HUMAN (266-846): 1.3e-35: 148: 11.70		EP300_HUMAN (13-430): 1.85e-13: 77.7: 8.50
+	Hs
		1056910 MDC1_HUMAN (92-849): 3.75e-17: 89.2: 11.38		CBP_HUMAN (5-492): 1.07e-29: 130: 12.88
+	Hs
		1172508 Q6ZTM8_HUMAN (43-522): 2.09e-09: 63.1: 10.22		CBP_HUMAN (5-492): 1.07e-29: 130: 12.88
+	Hs
		152675 KMT2D_HUMAN (111-821): 4.93e-09: 62.7: 10.67		CBP_HUMAN (5-492): 1.07e-29: 130: 12.88
+	Hs
		1079724 CIC_HUMAN (304-865): 4.13e-11: 69.3: 10.42		USF2_HUMAN (173-408): 4.77e-28: 118: 19.42
+	Hs
		998826 SRCAP_HUMAN (92-880): 3.35e-22: 105: 12.04		EP300_HUMAN (13-430): 1.85e-13: 77.7: 8.50
+	Hs
		1300954 CIC_HUMAN (304-865): 4.13e-11: 69.3: 10.42		MLXPL_HUMAN (94-426): 5.27e-24: 111: 16.02
+	Hs
		607835 CIC_HUMAN (304-865): 4.13e-11: 69.3: 10.42		USF1_HUMAN (223-408): 4.79e-26: 111: 20.20
+	Hs
		998710 MDC1_HUMAN (92-849): 3.75e-17: 89.2: 11.38		EP300_HUMAN (13-430): 1.85e-13: 77.7: 8.50
+	Dm
		113976 M9PB30_DROME (338-877): 6.65e-21: 101: 10.70		M9PB30_DROME (2-452): 3.59e-09: 63.8: 11.02
+	Mm
		1351630 PCLO_MOUSE (1-834): 1.98e-17: 90.1: 10.89		PCLO_MOUSE (13-412): 8.69e-11: 68.8: 11.55
+	Hs
		152667 KMT2D_HUMAN (111-821): 4.93e-09: 62.7: 10.67		KMT2C_HUMAN (15-528): 4.71e-13: 76.5: 10.09
+	Hs
		124053 CIC_HUMAN (304-865): 4.13e-11: 69.3: 10.42		SPT5H_HUMAN (136-326): 1.29e-10: 68: 9.90
+	Hs
		123781 KMT2D_HUMAN (111-821): 4.93e-09: 62.7: 10.67		SPT5H_HUMAN (136-326): 1.29e-10: 68: 9.90
+	Hs
		124057 MINT_HUMAN (6-818): 8.85e-09: 62: 9.92		SPT5H_HUMAN (136-326): 1.29e-10: 68: 9.90