Protein: MCAF1
Activating transcription factor 7-interacting protein 1 (ATF-interacting protein) (ATF-IP) (ATF7-interacting protein) (ATFa-associated modulator) (hAM) (MBD1-containing chromatin-associated factor 1) (P621)

Gene: MCAF1, ATF7IP
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q6VMQ6

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003712 - transcription coregulator activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1065633

SETB1
Histone-lysine N-methyltransferase SETDB1

5

11

Small-scale

0.721

High

435126

SP1
Transcription factor Sp1

4

11

Small-scale

0.703

High

1167135

MBD1
Methyl-CpG-binding domain protein 1

3

7

Small-scale

0.672

High

1167110

AL14E
ARL14 effector protein

3

2

High-throughput

0.671

High

1167109

RYBP
RING1 and YY1-binding protein

3

2

High-throughput

0.667

High

267659

TADA3
Transcriptional adapter 3

3

0

High-throughput

0.638

High

203719

SUV91
Histone-lysine N-methyltransferase SUV39H1

2

4

High-throughput

0.628

High

772026

VHL
von Hippel-Lindau disease tumor suppressor

2

1

High-throughput

0.628

High

1167106

YAF2
YY1-associated factor 2

2

2

High-throughput

0.628

High

1167115

EHMT2
Histone-lysine N-methyltransferase EHMT2

2

13

High-throughput

0.606

High

902640

SUMO2
Small ubiquitin-related modifier 2

2

6

High-throughput

0.602

High

1035480

SMAD4
Mothers against decapentaplegic homolog 4

2

5

High-throughput

0.595

High

1167116

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

9

High-throughput

0.552

High

1167134

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

Small-scale

0.549

High

281002

KRT38
Keratin, type I cuticular Ha8

1

3

High-throughput

0.536

High

358803

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.536

High

361226

TNNC2
Troponin C, skeletal muscle

1

7

High-throughput

0.536

High

647613

MK03
Mitogen-activated protein kinase 3

1

4

High-throughput

0.536

High

941074

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.536

High

949819

CBX1
Chromobox protein homolog 1

1

8

High-throughput

0.536

High

1029258

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

2

High-throughput

0.536

High

1077238

ZN174
Zinc finger protein 174

1

1

High-throughput

0.536

High

1080870

HSPB2
Heat shock protein beta-2

1

3

High-throughput

0.536

High

1167108

PIAS4
E3 SUMO-protein ligase PIAS4

1

3

High-throughput

0.536

High

953087

PR20A
Proline-rich protein 20A

2

1

High-throughput

0.533

High

971229

H11
Histone H1.1

1

5

High-throughput

0.515

High

1062359

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

1137448

MCAF2
Activating transcription factor 7-interacting protein 2

1

0

High-throughput

0.513

High

1167133

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

449753

HMGB1
High mobility group protein B1

1

20

Small-scale

0.508

High

1167128

DISC1
Disrupted in schizophrenia 1 protein

1

1

Small-scale

0.508

High

952972

PR20E
Proline-rich protein 20E

2

1

High-throughput

0.504

High

556896

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

High-throughput

0.481

High

930269

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.481

High

1016080

SRBP2
Sterol regulatory element-binding protein 2

1

17

High-throughput

0.481

High

1167113

CBP
CREB-binding protein

1

16

Small-scale

0.481

High

179694

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

9

High-throughput

0.479

High

201859

HXA2
Homeobox protein Hox-A2

1

14

High-throughput

0.479

High

316921

KLF8
Krueppel-like factor 8

1

19

High-throughput

0.479

High

386954

P53
Cellular tumor antigen p53

1

15

High-throughput

0.479

High

507453

ERG
Transcriptional regulator ERG

1

19

High-throughput

0.479

High

553001

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

584613

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

6

Small-scale

0.479

High

595935

HNF1A
Hepatocyte nuclear factor 1-alpha

1

15

High-throughput

0.479

High

624937

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.479

High

632784

TYY1
Transcriptional repressor protein YY1

1

6

High-throughput

0.479

High

664097

T2EB
Transcription initiation factor IIE subunit beta

1

2

Small-scale

0.479

High

720750

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

727546

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

727764

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

782576

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

884188

KLF3
Krueppel-like factor 3

1

19

High-throughput

0.479

High

967241

EWS
RNA-binding protein EWS

1

10

High-throughput

0.479

High

1027070

CBX3
Chromobox protein homolog 3

1

8

High-throughput

0.479

High

1167104

NAA40
N-alpha-acetyltransferase 40

1

6

High-throughput

0.479

High

1167105

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

1167107

SLX4
Structure-specific endonuclease subunit SLX4

1

16

High-throughput

0.479

High

1167111

NUP43
Nucleoporin Nup43

1

16

High-throughput

0.479

High

1167112

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1167117

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1167130

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

3

High-throughput

0.479

High

1167132

ZMYM2
Zinc finger MYM-type protein 2

1

3

High-throughput

0.479

High

1167140

KLF12
Krueppel-like factor 12

1

19

High-throughput

0.479

High

1167142

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.479

High

574159

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

0

Small-scale

0.458

High

664021

T2EA
General transcription factor IIE subunit 1

1

0

Small-scale

0.458

High

1167143

CDY2
Testis-specific chromodomain protein Y 2

1

0

High-throughput

0.458

High

172679

LAMA5
Laminin subunit alpha-5

1

2

High-throughput

0.457

High

261286

FLNB
Filamin-B

1

8

High-throughput

0.457

High

403657

AP2A
Transcription factor AP-2-alpha

1

1

High-throughput

0.457

High

729301

VGFR3
Vascular endothelial growth factor receptor 3

1

7

High-throughput

0.457

High

865052

TTC3
E3 ubiquitin-protein ligase TTC3

1

13

High-throughput

0.457

High

891850

ACTB
Actin, cytoplasmic 1

1

14

High-throughput

0.457

High

898363

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.457

High

929904

ACTG
Actin, cytoplasmic 2

1

14

High-throughput

0.457

High

957581

PKD1
Polycystin-1

1

2

High-throughput

0.457

High

963354

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

12

High-throughput

0.457

High

988959

FMR1
Fragile X messenger ribonucleoprotein 1

1

11

High-throughput

0.457

High

1040752

PEX6
Peroxisomal ATPase PEX6

1

1

High-throughput

0.457

High

1056581

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

10

High-throughput

0.457

High

1080647

ZBTB6
Zinc finger and BTB domain-containing protein 6

1

4

High-throughput

0.457

High

1117621

SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

1

2

High-throughput

0.457

High

1149495

Z518A
Zinc finger protein 518A

1

1

High-throughput

0.457

High

1167119

CP250
Centrosome-associated protein CEP250

1

9

High-throughput

0.457

High

1167123

KI13A
Kinesin-like protein KIF13A

1

5

High-throughput

0.457

High

1167124

SENP3
Sentrin-specific protease 3

1

2

High-throughput

0.457

High

1167126

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.457

High

1167127

HEYL
Hairy/enhancer-of-split related with YRPW motif-like protein

1

1

High-throughput

0.457

High

1167138

DMTF1
Cyclin-D-binding Myb-like transcription factor 1

1

6

High-throughput

0.457

High

1167144

PIAS3
E3 SUMO-protein ligase PIAS3

1

3

High-throughput

0.457

High

993888

PCDH1
Protocadherin-1

1

0

High-throughput

0.438

High

1165023

CSPG4
Chondroitin sulfate proteoglycan 4

1

0

High-throughput

0.438

High

1167118

MTNA
Methylthioribose-1-phosphate isomerase

1

0

High-throughput

0.438

High

1167122

ZN350
Zinc finger protein 350

1

0

High-throughput

0.438

High

1167141

GMEB1
Glucocorticoid modulatory element-binding protein 1

1

0

High-throughput

0.438

High

1002046

ARL16
ADP-ribosylation factor-like protein 16

1

1

High-throughput

0.437

High

1167103

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

441069

CO4A2

1

1

High-throughput

0.417

High

502845

LAMC1
Laminin subunit gamma-1

1

1

High-throughput

0.417

High

793359

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.417

High

877547

CAD11
Cadherin-11

1

4

High-throughput

0.417

High

1028133

PAPP1
Pappalysin-1

1

4

High-throughput

0.417

High

1081777

LAMA4
Laminin subunit alpha-4

1

2

High-throughput

0.417

High

1165276

SUSD1
Sushi domain-containing protein 1

1

5

High-throughput

0.417

High

1167120

PAPP2
Pappalysin-2

1

4

High-throughput

0.417

High

1167129

Q9NXG9
cDNA FLJ20259 fis, clone COLF7443

1

3

High-throughput

0.417

High

1167131

RRBP1
Ribosome-binding protein 1

1

12

High-throughput

0.417

High

1167137

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

10

High-throughput

0.417

High

353786

IGHG2
Immunoglobulin heavy constant gamma 2

1

2

High-throughput

0.407

High

270057

RF1M
Peptide chain release factor 1, mitochondrial

1

0

High-throughput

0.279

Low

307628

STBD1
Starch-binding domain-containing protein 1

1

0

High-throughput

0.238

Low

354492

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.238

Low

555062

ANPRA
Atrial natriuretic peptide receptor 1

1

0

High-throughput

0.238

Low

1069009

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.238

Low

1083163

PSG3
Pregnancy-specific beta-1-glycoprotein 3

1

0

High-throughput

0.238

Low

1085206

PRSS8
Prostasin

1

0

High-throughput

0.238

Low

1167114

PKHB2
Pleckstrin homology domain-containing family B member 2

1

0

High-throughput

0.238

Low

1167121

CADM1
Cell adhesion molecule 1

1

0

High-throughput

0.238

Low

1167125

EPG5
Ectopic P granules protein 5 homolog

1

0

High-throughput

0.238

Low

1167136

S12A4
Solute carrier family 12 member 4

1

0

High-throughput

0.238

Low

1167139

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024