HitPredict

Interactor 1: MCM4 (P30665)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Cell division control protein 54)
Gene: MCM4

Interactor 2: MCM6 (P53091)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (Minichromosome maintenance protein 6)
Gene: MCM6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 24805245, 25172955, 37968396, 22250202, 22421151, 23499444, 26255844, 15723534, 26686640, 28191893, 27397685, 26250113, 32075754, 18662997, 19661920, 19896182, 38776358, 39838174, 22433841, 23499531 and 2 others

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Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid, biochemical, pull down, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM6_C, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM~MCM4_WHD, MCM4_WHD~MCM_lid, MCM6_C~MCM_lid, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 15 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 933
Sc

1 1017
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Last updated: 11Aug2025