HitPredict

Interactor 1: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Interactor 2: EFHD2 (Q96C19)
EF-hand domain-containing protein D2 (Swiprosin-1)
Gene: EFHD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1976 Hs			1 240
+	Ce
		104561 G5EBY3_CAEEL (23-1927): 0: 1312: 45.99		CALM_CAEEL (47-160): 6.99e-22: 89.7: 23.02
+	Mm
		1143166 MYH10_MOUSE (1-1976): 0: 1112: 99.09		Q6ZWQ9_MOUSE (60-228): 9.35e-39: 134: 21.30
+	Hs
		159550 MYH10_HUMAN (1-1976): 0: 1106: 100.00		ML12B_HUMAN (71-179): 5.38e-35: 124: 29.36
+	Hs
		580615 MYH10_HUMAN (1-1976): 0: 1106: 100.00		ML12A_HUMAN (72-179): 3.78e-34: 122: 29.63
+	Hs
		624342 MYH10_HUMAN (1-1976): 0: 1106: 100.00		MYL9_HUMAN (72-179): 2.12e-33: 120: 29.63
+	Hs
		724955 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		EFHD2_HUMAN (1-240): 9.13e-68: 210: 100.00
+	Hs
		159551 MYH11_HUMAN (805-1976): 1.82e-68: 259: 18.21		ML12B_HUMAN (71-179): 5.38e-35: 124: 29.36
+	Dm
		1303398 MYSN_DROME (985-1974): 1.71e-56: 219: 16.49		EFHD2_DROME (42-240): 2.62e-49: 162: 54.73
+	Hs
		580616 MYH11_HUMAN (805-1976): 1.82e-68: 259: 18.21		ML12A_HUMAN (72-179): 3.78e-34: 122: 29.63
+	Hs
		159549 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		ML12B_HUMAN (71-179): 5.38e-35: 124: 29.36
+	Hs
		580614 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		ML12A_HUMAN (72-179): 3.78e-34: 122: 29.63
+	Hs
		624341 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MYL9_HUMAN (72-179): 2.12e-33: 120: 29.63
+	Hs
		159595 MYH14_HUMAN (889-1974): 4.36e-57: 221: 18.29		ML12B_HUMAN (71-179): 5.38e-35: 124: 29.36
+	Hs
		580665 MYH14_HUMAN (889-1974): 4.36e-57: 221: 18.29		ML12A_HUMAN (72-179): 3.78e-34: 122: 29.63
+	Hs
		501101 MYH1_HUMAN (930-1976): 9.74e-66: 249: 18.26		MLRV_HUMAN (66-211): 2.16e-20: 86.5: 23.13
+	Hs
		648467 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		CALL3_HUMAN (47-160): 7.25e-19: 82: 19.84
+	Dm
		773034 MYSN_DROME (985-1974): 1.71e-56: 219: 16.49		SQH_DROME (67-179): 4.46e-29: 109: 24.78
+	Ce
		361122 MYO1_CAEEL (734-1731): 2.7e-55: 216: 17.00		MLR1_CAEEL (84-185): 1.47e-18: 81.8: 24.51
+	Ce
		361123 MYO1_CAEEL (734-1731): 2.7e-55: 216: 17.00		MLR2_CAEEL (84-185): 1.85e-18: 81.5: 24.51
+	Ce
		361111 MYO4_CAEEL (732-1537): 3.32e-37: 156: 15.27		MLR1_CAEEL (84-185): 1.47e-18: 81.8: 24.51