HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: SP130 (Q9H0E3)
Histone deacetylase complex subunit SAP130 (130 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p130)
Gene: SAP130

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 1048
+	Hs
		1429906 NANOG_HUMAN (138-316): 5.92e-39: 141: 26.46		SP130_HUMAN (1-1048): 3.89e-131: 425: 100.00
+	Mm
		629350 PO5F1_MOUSE (32-327): 7.6e-31: 121: 15.15		SP130_MOUSE (27-1048): 1.24e-123: 405: 89.97
+	Hs
		725285 TLX1_HUMAN (1-330): 5.03e-61: 199: 100.00		KMT2C_HUMAN (10-987): 6.15e-18: 92.4: 10.33
+	Hs
		725306 TLX1_HUMAN (1-330): 5.03e-61: 199: 100.00		CIC_HUMAN (2-856): 1.06e-11: 71.6: 9.79
+	Hs
		226574 TLX2_HUMAN (4-327): 1.06e-41: 148: 51.79		KMT2C_HUMAN (10-987): 6.15e-18: 92.4: 10.33
+	Hs
		226588 TLX2_HUMAN (4-327): 1.06e-41: 148: 51.79		CIC_HUMAN (2-856): 1.06e-11: 71.6: 9.79
+	Hs
		225064 TLX3_HUMAN (11-325): 3.91e-31: 120: 48.25		KMT2C_HUMAN (10-987): 6.15e-18: 92.4: 10.33
+	Hs
		942450 GSC_HUMAN (19-285): 1.33e-30: 118: 20.97		KMT2C_HUMAN (10-987): 6.15e-18: 92.4: 10.33
+	Hs
		1360900 NANOG_HUMAN (138-316): 5.92e-39: 141: 26.46		MUC16_HUMAN (14-885): 3.36e-09: 63.5: 11.01
+	Hs
		225087 TLX3_HUMAN (11-325): 3.91e-31: 120: 48.25		CIC_HUMAN (2-856): 1.06e-11: 71.6: 9.79
+	Hs
		604850 HXB9_HUMAN (17-266): 2.31e-31: 120: 18.00		CIC_HUMAN (2-856): 1.06e-11: 71.6: 9.79
+	Hs
		634873 HXA5_HUMAN (53-276): 8.07e-31: 119: 23.21		CIC_HUMAN (2-856): 1.06e-11: 71.6: 9.79
+	Mm
		629359 PO5F1_MOUSE (32-327): 7.6e-31: 121: 15.15		KMT2C_MOUSE (9-866): 5.39e-10: 66.2: 8.96
+	Hs
		1033736 PO5F1_HUMAN (31-327): 1.03e-30: 120: 17.00		MUC16_HUMAN (14-885): 3.36e-09: 63.5: 11.01
+	Hs
		1288841 ZFHX4_HUMAN (202-287): 2.44e-11: 66.9: 20.93		CIC_HUMAN (2-856): 1.06e-11: 71.6: 9.79