HitPredict

Interactor 1: CXG1 (P36383)
Gap junction gamma-1 protein (Connexin-45) (Cx45) (Gap junction alpha-7 protein)
Gene: GJC1

Interactor 2: PI2R (P43119)
Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor)
Gene: PTGIR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007267 - cell-cell signaling
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 396 Hs			1 386
+	Hs
		429067 CXG2_HUMAN (1-396): 2.39e-145: 421: 45.13		ADRB2_HUMAN (5-376): 1.54e-72: 233: 14.29
+	Hs
		723252 CXG2_HUMAN (1-396): 2.39e-145: 421: 45.13		PE2R4_HUMAN (7-337): 2.33e-68: 225: 33.60
+	Hs
		600865 CXB2_HUMAN (1-256): 5.05e-110: 323: 33.33		TA2R_HUMAN (7-325): 1.04e-87: 270: 31.44
+	Hs
		816628 CXA8_HUMAN (2-390): 1.38e-120: 358: 31.59		QRFPR_HUMAN (5-355): 2.49e-62: 207: 14.52
+	Hs
		661147 CXB2_HUMAN (1-256): 5.05e-110: 323: 33.33		APJ_HUMAN (3-357): 6.16e-64: 210: 15.20
+	Hs
		716552 CXA4_HUMAN (2-343): 2.15e-106: 318: 34.84		OPRM_HUMAN (1-355): 8.9e-63: 208: 13.89
+	Hs
		716554 CXA4_HUMAN (2-343): 2.15e-106: 318: 34.84		OPRK_HUMAN (4-321): 2.75e-58: 196: 16.62
+	Hs
		566926 CXA1_HUMAN (2-362): 1.36e-138: 402: 33.25		FSHR_HUMAN (25-350): 1.82e-12: 70.9: 17.73
+	Hs
		661153 CXB2_HUMAN (1-256): 5.05e-110: 323: 33.33		Q0VAB0_HUMAN (7-141): 1.92e-27: 110: 30.00