HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 30344098, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 1475
+	Hs
		834574 PP1A_HUMAN (1-323): 0: 579: 90.66		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Hs
		905894 PP1A_HUMAN (1-323): 0: 579: 90.66		MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00
+	Hs
		930846 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00
+	Hs
		738105 PP1G_HUMAN (1-323): 0: 603: 100.00		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		906185 PP1A_HUMAN (1-323): 0: 579: 90.66		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		738130 PP1G_HUMAN (1-323): 0: 603: 100.00		SRRM2_HUMAN (145-1251): 4.61e-12: 73.7: 9.24
+	Hs
		906621 PP1B_HUMAN (1-322): 0: 560: 86.89		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Dm
		113980 PP1B_DROME (1-323): 0: 552: 82.48		M9PB30_DROME (77-757): 6.74e-17: 89.5: 9.05
+	Hs
		931030 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89