HitPredict

Interactor 1: PTPRB (B2RU80)
Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP)
Gene: PTPRB

Interactor 2: CADH5 (P55284)
Cadherin-5 (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)
Gene: Cdh5

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	21857650, 12234928
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type	physical association, dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1998 Mm			1 784
+	Hs
		658809 PTPRB_HUMAN (1-1998): 0: 1310: 85.89		CADH5_HUMAN (31-783): 0: 735: 75.83
+	Hs
		618215 PTPRB_HUMAN (1-1998): 0: 1310: 85.89		CADH2_HUMAN (256-753): 9.69e-42: 166: 14.85
+	Hs
		522579 PTPRF_HUMAN (12-998): 2.31e-93: 339: 12.70		CADH1_HUMAN (18-780): 0: 628: 31.20
+	Mm
		504798 PTPRQ_MOUSE (1219-1696): 3.59e-22: 107: 11.01		CADH5_MOUSE (1-784): 0: 751: 100.00
+	Hs
		556048 PTPRJ_HUMAN (289-1206): 9.04e-46: 184: 12.65		CADH1_HUMAN (18-780): 0: 628: 31.20
+	Hs
		555875 PTPRD_HUMAN (3-476): 6.48e-44: 178: 14.12		CADH1_HUMAN (18-780): 0: 628: 31.20
+	Hs
		556057 PTPRS_HUMAN (3-455): 1.63e-36: 154: 14.73		CADH1_HUMAN (18-780): 0: 628: 31.20
+	Mm
		486802 PTPRQ_MOUSE (1219-1696): 3.59e-22: 107: 11.01		CADH1_MOUSE (23-780): 0: 595: 30.26
+	Hs
		522763 PTPRF_HUMAN (12-998): 2.31e-93: 339: 12.70		PCDG5_HUMAN (2-470): 2.82e-93: 314: 19.96
+	Hs
		522743 PTPRF_HUMAN (12-998): 2.31e-93: 339: 12.70		PCDBG_HUMAN (264-759): 1.2e-75: 262: 17.82
+	Hs
		614647 PTPRA_HUMAN (1688-1967): 1.66e-102: 351: 35.23		CADH2_HUMAN (256-753): 9.69e-42: 166: 14.85
+	Hs
		658948 PTPRD_HUMAN (3-476): 6.48e-44: 178: 14.12		PCDG6_HUMAN (3-470): 1.65e-93: 314: 19.84
+	Rn
		1225811 PTPRF_RAT (6-744): 1.34e-71: 269: 14.07		CADH2_RAT (4-468): 3.06e-59: 218: 19.36
+	Hs
		1102778 PTPRS_HUMAN (3-455): 1.63e-36: 154: 14.73		PCDG6_HUMAN (3-470): 1.65e-93: 314: 19.84
+	Hs
		658946 PTPRD_HUMAN (3-476): 6.48e-44: 178: 14.12		PCDB6_HUMAN (262-759): 1.08e-78: 271: 16.26
+	Hs
		658936 PTPRD_HUMAN (3-476): 6.48e-44: 178: 14.12		PCDBG_HUMAN (264-759): 1.2e-75: 262: 17.82
+	Hs
		618248 PTPRJ_HUMAN (289-1206): 9.04e-46: 184: 12.65		CADH2_HUMAN (256-753): 9.69e-42: 166: 14.85
+	Mm
		504795 PTPRQ_MOUSE (1219-1696): 3.59e-22: 107: 11.01		CADH2_MOUSE (4-468): 2.43e-59: 219: 19.36
+	Hs
		471719 PTPRC_HUMAN (1704-1978): 5.31e-25: 116: 28.43		CADH2_HUMAN (256-753): 9.69e-42: 166: 14.85
+	Dm
		194862 LAR_DROME (2-692): 2.08e-52: 206: 13.33		CADN_DROME (103-505): 9.86e-12: 71.2: 26.71