HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: RV167 (P39743)
Reduced viability upon starvation protein 167
Gene: RVS167

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.862

Property	Details
Experiments	11489916, 19841731, 14761940
Identification Methods	two hybrid, pull down, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0006897 - endocytosis GO:0030479 - actin cortical patch GO:0043332 - mating projection tip
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1244 Sc			1 482
+	Sc
		744921 SLA1_YEAST (1-1244): 6.03e-180: 566: 100.00		MYO5_YEAST (6-479): 7.5e-43: 164: 11.07
+	Sc
		744824 SLA1_YEAST (1-1244): 6.03e-180: 566: 100.00		MYO3_YEAST (6-482): 3.58e-39: 153: 10.22
+	Sc
		744879 SLA1_YEAST (1-1244): 6.03e-180: 566: 100.00		LSB3_YEAST (310-479): 5.14e-28: 118: 25.42
+	Sc
		744809 SLA1_YEAST (1-1244): 6.03e-180: 566: 100.00		YSC84_YEAST (384-480): 7.31e-28: 117: 30.93
+	Rn
		148406 SYNJ1_RAT (481-973): 1.68e-11: 71.1: 8.42		BIN1_RAT (3-481): 1.84e-50: 183: 12.10
+	Hs
		215960 SYNJ1_HUMAN (336-830): 1.49e-10: 68: 11.25		PACN2_HUMAN (5-481): 5.31e-51: 182: 15.48
+	Sc
		739093 PAN1_YEAST (842-1042): 1.09e-14: 81.7: 23.72		MYO5_YEAST (6-479): 7.5e-43: 164: 11.07
+	Hs
		215920 SYNJ1_HUMAN (336-830): 1.49e-10: 68: 11.25		MYO1E_HUMAN (5-480): 2.63e-46: 174: 14.55
+	Ce
		73269 G5EBN5_CAEEL (889-1243): 1.51e-11: 71.4: 9.30		SH3GH_CAEEL (75-479): 1.99e-46: 167: 18.43
+	Sc
		739061 PAN1_YEAST (842-1042): 1.09e-14: 81.7: 23.72		MYO3_YEAST (6-482): 3.58e-39: 153: 10.22
+	Rn
		204410 SYNJ1_RAT (481-973): 1.68e-11: 71.1: 8.42		SH3G2_RAT (84-480): 7.38e-42: 154: 15.00
+	Mm
		92772 D3Z656_MOUSE (491-923): 2.6e-11: 70.7: 9.01		SH3G2_MOUSE (84-480): 1.38e-41: 153: 14.75
+	Hs
		215946 SYNJ1_HUMAN (336-830): 1.49e-10: 68: 11.25		SH3G2_HUMAN (84-480): 1.27e-41: 153: 14.25
+	Rn
		205732 SYNJ1_RAT (481-973): 1.68e-11: 71.1: 8.42		SH3G1_RAT (85-480): 5.03e-40: 149: 13.78
+	Hs
		215948 SYNJ1_HUMAN (336-830): 1.49e-10: 68: 11.25		PACN1_HUMAN (5-480): 1.28e-39: 150: 12.78
+	Hs
		215945 SYNJ1_HUMAN (336-830): 1.49e-10: 68: 11.25		SH3G1_HUMAN (85-480): 4.36e-40: 149: 14.54
+	Hs
		215943 SYNJ1_HUMAN (336-830): 1.49e-10: 68: 11.25		SH3Y1_HUMAN (373-480): 7.69e-27: 112: 31.30
+	Hs
		215925 SYNJ1_HUMAN (336-830): 1.49e-10: 68: 11.25		ITSN1_HUMAN (192-482): 9.76e-20: 94.9: 16.67
+	Rn
		148393 SYNJ1_RAT (481-973): 1.68e-11: 71.1: 8.42		AMPH_RAT (290-481): 4.37e-10: 64.1: 14.35
+	Hs
		215908 SYNJ1_HUMAN (336-830): 1.49e-10: 68: 11.25		AMPH_HUMAN (319-480): 4.65e-11: 67.1: 15.43