HitPredict

Interactor 1: UBC2 (P35129)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Lethal protein 70) (Ubiquitin carrier protein 2) (Ubiquitin-protein ligase 2)
Gene: let-70

Interactor 2: Q8WTJ8 (Q8WTJ8)
RING-type domain-containing protein
Gene: grif-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.743

Property	Details
Experiments	18692475, unassigned701
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Ce			1 305
+	Hs
		1420598 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRIM2_HUMAN (7-287): 1.46e-45: 165: 17.42
+	Hs
		1384952 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRI43_HUMAN (6-292): 2.6e-46: 163: 14.87
+	Hs
		1439327 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRI39_HUMAN (10-291): 1.69e-45: 162: 15.81
+	Hs
		1420579 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRIM5_HUMAN (6-295): 2.31e-44: 159: 12.71
+	Hs
		906650 UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12		TRI26_HUMAN (6-292): 1.02e-44: 161: 12.16
+	Hs
		623204 UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12		RO52_HUMAN (6-292): 7.53e-45: 160: 15.54
+	Hs
		279076 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRIM3_HUMAN (14-273): 2.08e-42: 157: 15.85
+	Hs
		572291 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRI27_HUMAN (6-292): 1.14e-43: 157: 14.53
+	Hs
		279031 UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12		TRIM3_HUMAN (14-273): 2.08e-42: 157: 15.85
+	Hs
		571903 UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12		TRI27_HUMAN (6-292): 1.14e-43: 157: 14.53
+	Hs
		1490991 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRI17_HUMAN (11-291): 1.44e-41: 151: 13.79
+	Hs
		1460665 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRIM1_HUMAN (7-298): 2.89e-40: 150: 16.16
+	Hs
		1233123 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		Q6GX22_HUMAN (10-298): 1.13e-39: 148: 16.01
+	Hs
		1458960 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRI10_HUMAN (6-293): 2.31e-40: 148: 13.42
+	Hs
		186599 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRI18_HUMAN (10-301): 3.32e-39: 147: 14.08
+	Hs
		906652 UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12		TRI32_HUMAN (6-280): 1.56e-39: 148: 18.48
+	Hs
		186519 UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12		TRI18_HUMAN (10-301): 3.32e-39: 147: 14.08
+	Hs
		783461 UB2D4_HUMAN (1-147): 1e-83: 243: 92.52		TRI23_HUMAN (12-226): 1.23e-18: 88.1: 17.57
+	Hs
		783205 UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12		TRI23_HUMAN (12-226): 1.23e-18: 88.1: 17.57
+	Hs
		906688 UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12		SH3R1_HUMAN (9-174): 1.05e-15: 79.3: 16.57