HitPredict

Interactor 1: CCNF (P41002)
Cyclin-F (F-box only protein 1)
Gene: CCNF

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33729478, 36114006
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051726 - regulation of cell cycle
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 786 Hs			1 156
+	Hs
		779260 CCNF_HUMAN (1-786): 0: 952: 100.00		ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37
+	Hs
		779322 CCNF_HUMAN (1-786): 0: 952: 100.00		ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13
+	Hs
		257577 CCNF_HUMAN (1-786): 0: 952: 100.00		ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25
+	Hs
		779707 CCNF_HUMAN (1-786): 0: 952: 100.00		ANKH1_HUMAN (68-155): 3.32e-18: 82.3: 19.32
+	Hs
		276148 CCNF_HUMAN (1-786): 0: 952: 100.00		PSD10_HUMAN (1-85): 4.57e-12: 63.1: 23.86
+	Hs
		780233 CCNF_HUMAN (1-786): 0: 952: 100.00		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21
+	Hs
		166893 CCNF_HUMAN (1-786): 0: 952: 100.00		ANR28_HUMAN (82-155): 3.69e-09: 56.1: 16.22
+	Hs
		624558 CCNE1_HUMAN (177-567): 1.06e-93: 300: 16.14		CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00
+	Hs
		624559 CCNE1_HUMAN (177-567): 1.06e-93: 300: 16.14		CDN2B_HUMAN (3-136): 4.71e-52: 163: 81.34
+	Hs
		624560 CCNE1_HUMAN (177-567): 1.06e-93: 300: 16.14		CDN2C_HUMAN (21-135): 1.37e-25: 97.4: 28.21