HitPredict

Interactor 1: SET3 (P36124)
SET domain-containing protein 3
Gene: SET3

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 751 Sc			1 889
+	Sc
		743080 SET3_YEAST (1-751): 0: 681: 100.00		STH1_YEAST (275-377): 2.5e-11: 69.8: 24.27
+	Sc
		781785 SET3_YEAST (1-751): 0: 681: 100.00		RSC4_YEAST (34-128): 1.92e-10: 66.7: 27.84
+	Hs
		1201960 NSD3_HUMAN (123-556): 2.53e-73: 262: 13.43		BRDT_HUMAN (1-659): 1.51e-71: 256: 13.36
+	Hs
		355526 NSD2_HUMAN (114-556): 6.26e-75: 266: 13.25		BRD3_HUMAN (7-385): 5.44e-69: 245: 15.92
+	Hs
		1141267 NSD1_HUMAN (122-556): 7.02e-74: 264: 13.59		BRD3_HUMAN (7-385): 5.44e-69: 245: 15.92
+	Hs
		1141291 NSD3_HUMAN (123-556): 2.53e-73: 262: 13.43		BRD3_HUMAN (7-385): 5.44e-69: 245: 15.92
+	Hs
		1041527 KMT2A_HUMAN (35-480): 4.46e-62: 229: 14.92		BRD3_HUMAN (7-385): 5.44e-69: 245: 15.92
+	Hs
		1141295 SETD5_HUMAN (52-750): 3.89e-52: 198: 13.74		BRD3_HUMAN (7-385): 5.44e-69: 245: 15.92
+	Mm
		1189456 NSD2_MOUSE (114-556): 5.65e-75: 266: 13.25		SMCA4_MOUSE (9-122): 2.16e-30: 131: 30.17
+	Hs
		355431 NSD2_HUMAN (114-556): 6.26e-75: 266: 13.25		BRD2_HUMAN (2-255): 7.8e-29: 125: 15.89
+	Hs
		903474 NSD3_HUMAN (123-556): 2.53e-73: 262: 13.43		SMCA4_HUMAN (9-122): 7.81e-29: 126: 29.92
+	Hs
		674318 NSD3_HUMAN (123-556): 2.53e-73: 262: 13.43		BRD2_HUMAN (2-255): 7.8e-29: 125: 15.89
+	Hs
		903248 NSD3_HUMAN (123-556): 2.53e-73: 262: 13.43		SMCA2_HUMAN (9-150): 8.61e-28: 123: 24.07
+	Hs
		259273 NSD2_HUMAN (114-556): 6.26e-75: 266: 13.25		BRD4_HUMAN (2-329): 6.26e-26: 117: 12.31
+	Mm
		1297458 NSD2_MOUSE (114-556): 5.65e-75: 266: 13.25		BRD4_MOUSE (2-329): 1.95e-25: 115: 12.50
+	Hs
		260413 NSD3_HUMAN (123-556): 2.53e-73: 262: 13.43		BRD4_HUMAN (2-329): 6.26e-26: 117: 12.31
+	Hs
		903135 KMT2A_HUMAN (35-480): 4.46e-62: 229: 14.92		SMCA2_HUMAN (9-150): 8.61e-28: 123: 24.07
+	Hs
		259825 KMT2A_HUMAN (35-480): 4.46e-62: 229: 14.92		BRD4_HUMAN (2-329): 6.26e-26: 117: 12.31
+	Hs
		260422 SETD5_HUMAN (52-750): 3.89e-52: 198: 13.74		BRD4_HUMAN (2-329): 6.26e-26: 117: 12.31
+	Hs
		260412 SETD2_HUMAN (161-702): 3.58e-48: 186: 12.39		BRD4_HUMAN (2-329): 6.26e-26: 117: 12.31