Protein: SETD5
Histone-lysine N-methyltransferase SETD5 (EC 2.1.1.359) (EC 2.1.1.367) (SET domain-containing protein 5)

Gene: SETD5
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q9C0A6

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

938134

ANM2
Protein arginine N-methyltransferase 2

3

2

High-throughput

0.667

High

1292805

SKAP1
Src kinase-associated phosphoprotein 1

3

1

High-throughput

0.667

High

1205977

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

6

High-throughput

0.646

High

1322285

SPG16
Sperm-associated antigen 16 protein

1

7

High-throughput

0.618

High

250333

VINEX
Vinexin

2

2

High-throughput

0.606

High

1095795

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

3

High-throughput

0.606

High

396893

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1201889

PKHG4
Puratrophin-1

2

1

High-throughput

0.553

High

1090902

TRAF2
TNF receptor-associated factor 2

1

4

High-throughput

0.541

High

343804

LDOC1
Protein LDOC1

1

0

High-throughput

0.536

High

1065416

SSRP1
FACT complex subunit SSRP1

1

7

High-throughput

0.536

High

1391438

RMD5B
E3 ubiquitin-protein transferase RMND5B

1

1

High-throughput

0.536

High

1017745

PR20A
Proline-rich protein 20A

2

1

High-throughput

0.533

High

1230246

K1C40
Keratin, type I cytoskeletal 40

1

5

High-throughput

0.523

High

1340345

CEP70
Centrosomal protein of 70 kDa

1

2

High-throughput

0.523

High

1154586

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

1281381

DPPA2
Developmental pluripotency-associated protein 2

1

0

High-throughput

0.518

High

1053277

Q05BL1
TP53BP2 protein

1

8

High-throughput

0.515

High

1017604

PR20E
Proline-rich protein 20E

2

1

High-throughput

0.504

High

391451

FRIL
Ferritin light chain

1

2

High-throughput

0.489

High

1420657

FBLN5
Fibulin-5

1

3

High-throughput

0.489

High

1115605

ASPP2
Apoptosis-stimulating of p53 protein 2

1

9

High-throughput

0.481

High

130605

SPT5H
Transcription elongation factor SPT5

1

4

High-throughput

0.479

High

260422

BRD4
Bromodomain-containing protein 4

1

19

High-throughput

0.479

High

975925

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.479

High

1045740

TF65
Transcription factor p65

1

2

High-throughput

0.479

High

1141295

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

1408472

VRK1
Serine/threonine-protein kinase VRK1

1

2

High-throughput

0.479

High

1420658

XPO7
Exportin-7

1

3

High-throughput

0.479

High

157823

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.437

High

58928

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.407

High

1420659

NAGK
N-acetyl-D-glucosamine kinase

2

0

High-throughput

0.328

High


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Last updated: 11Aug2025