Interactor 1: RPN3 (P40016)
26S proteasome regulatory subunit RPN3
Gene: RPN3

Interactor 2: RPN6 (Q12377)
26S proteasome regulatory subunit RPN6 (Proteasome non-ATPase subunit 4)
Gene: RPN6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 11805826, 31848235, 12198498, 23911091, 24412063, 9741626, 10873636, 16554755, 16429126, 37968396
Identification Methods tandem affinity purification, cross-linking study, pull down, affinity chromatography technology, biochemical
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, RPN6_C_helix~Rpn3_C
Common GO terms GO:0000502 - proteasome complex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 523
Sc

1 434
+ Hs
+ Dm
+ Hs
+ Dm
+ Ce
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Dm
+ At
+ At
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025