HitPredict

Interactor 1: PRS4 (P48601)
26S proteasome regulatory subunit 4 (P26s4)
Gene: Rpt2

Interactor 2: Q9VUJ1 (Q9VUJ1)
Proteasome subunit beta
Gene: Prosbeta2

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 439 Dm			1 272
+	Sc
		625948 PRS10_YEAST (9-436): 8.69e-144: 419: 37.82		PSB2_YEAST (12-272): 2.18e-82: 249: 53.44
+	Hs
		906905 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSB7_HUMAN (1-268): 7.55e-86: 259: 63.27
+	At
		286460 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		PSA5A_ARATH (1-231): 2.06e-86: 259: 20.08
+	At
		1114627 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		PSA5B_ARATH (1-231): 4.42e-86: 258: 19.25
+	At
		1176526 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		PSB7B_ARATH (1-269): 5.99e-85: 256: 62.96
+	At
		188703 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		PSB7A_ARATH (1-269): 6.4e-85: 256: 60.95
+	Hs
		656193 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSA5_HUMAN (1-236): 2.98e-84: 253: 19.51
+	Dm
		820495 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		PSA5_DROME (1-237): 3.19e-81: 246: 17.67
+	At
		286458 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		PSA4A_ARATH (9-236): 9.86e-83: 250: 15.90
+	Hs
		156269 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSA7_HUMAN (7-235): 5.22e-78: 238: 21.85
+	Sc
		675428 PRS10_YEAST (9-436): 8.69e-144: 419: 37.82		PSB5_YEAST (18-232): 2.35e-70: 220: 27.19
+	Dm
		820480 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		Q7K148_DROME (38-229): 5.73e-72: 223: 31.61
+	Dm
		47601 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		A0AQH0_DROME (33-253): 2.31e-72: 222: 26.58
+	At
		188714 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		PSB5A_ARATH (6-249): 4.1e-74: 229: 28.16
+	Hs
		656582 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSB6_HUMAN (34-225): 5.81e-73: 225: 29.53
+	At
		1227660 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		PSB6_ARATH (30-233): 9.78e-74: 226: 30.24
+	Hs
		656694 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSB5_HUMAN (35-232): 4.35e-72: 223: 27.64
+	At
		188699 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		PSA2A_ARATH (7-236): 6.31e-70: 217: 18.64
+	Sc
		751173 PRS10_YEAST (9-436): 8.69e-144: 419: 37.82		PSB1_YEAST (39-228): 1.03e-27: 107: 31.94
+	Hs
		656104 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSB9_HUMAN (8-224): 2.27e-26: 104: 30.73