HitPredict

Interactor 1: KC1A (P48729)
Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)
Gene: CSNK1A1

Interactor 2: FA83B (Q5T0W9)
Protein FAM83B
Gene: FAM83B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	27684187, 35271311, 32707033, 23455922, 29789297
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, protein kinase assay, pull down, tandem affinity purification
Interaction Type	physical association, association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0007165 - signal transduction GO:0016020 - membrane GO:0045104 - intermediate filament cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 337 Hs			1 1011
+	Hs
		1132481 KC1AL_HUMAN (1-336): 3.69e-118: 346: 90.77		FA83B_HUMAN (1-1011): 0: 1931: 100.00
+	Hs
		830387 KC1E_HUMAN (9-311): 8.5e-115: 340: 74.26		FA83B_HUMAN (1-1011): 0: 1931: 100.00
+	Hs
		1170116 KC1AL_HUMAN (1-336): 3.69e-118: 346: 90.77		FA83H_HUMAN (1-287): 1.06e-125: 412: 46.92
+	Hs
		822065 KC1A_HUMAN (1-337): 1.03e-115: 340: 100.00		FA83H_HUMAN (1-287): 1.06e-125: 412: 46.92
+	Hs
		830400 KC1E_HUMAN (9-311): 8.5e-115: 340: 74.26		FA83H_HUMAN (1-287): 1.06e-125: 412: 46.92
+	Hs
		61980 KC1AL_HUMAN (1-336): 3.69e-118: 346: 90.77		FA83G_HUMAN (13-280): 2e-119: 387: 35.76
+	Hs
		61969 KC1A_HUMAN (1-337): 1.03e-115: 340: 100.00		FA83G_HUMAN (13-280): 2e-119: 387: 35.76
+	Hs
		61971 KC1E_HUMAN (9-311): 8.5e-115: 340: 74.26		FA83G_HUMAN (13-280): 2e-119: 387: 35.76
+	Hs
		1236896 KC1AL_HUMAN (1-336): 3.69e-118: 346: 90.77		FA83F_HUMAN (13-280): 8.01e-113: 359: 35.74
+	Hs
		822096 KC1A_HUMAN (1-337): 1.03e-115: 340: 100.00		FA83F_HUMAN (13-280): 8.01e-113: 359: 35.74
+	Hs
		1101621 KC1AL_HUMAN (1-336): 3.69e-118: 346: 90.77		FA83E_HUMAN (4-281): 4.25e-109: 349: 34.03
+	Hs
		1200456 KC1AL_HUMAN (1-336): 3.69e-118: 346: 90.77		FA83A_HUMAN (4-280): 1.01e-109: 349: 34.72
+	Hs
		1236905 KC1AL_HUMAN (1-336): 3.69e-118: 346: 90.77		FA83D_HUMAN (14-280): 1.96e-107: 348: 37.37
+	Hs
		1236903 KC1AL_HUMAN (1-336): 3.69e-118: 346: 90.77		FA83C_HUMAN (24-280): 7.36e-105: 346: 41.13
+	Hs
		822038 KC1A_HUMAN (1-337): 1.03e-115: 340: 100.00		FA83E_HUMAN (4-281): 4.25e-109: 349: 34.03
+	Hs
		822080 KC1A_HUMAN (1-337): 1.03e-115: 340: 100.00		FA83A_HUMAN (4-280): 1.01e-109: 349: 34.72
+	Hs
		830377 KC1E_HUMAN (9-311): 8.5e-115: 340: 74.26		FA83E_HUMAN (4-281): 4.25e-109: 349: 34.03
+	Hs
		830408 KC1E_HUMAN (9-311): 8.5e-115: 340: 74.26		FA83A_HUMAN (4-280): 1.01e-109: 349: 34.72
+	Hs
		830477 KC1E_HUMAN (9-311): 8.5e-115: 340: 74.26		FA83D_HUMAN (14-280): 1.96e-107: 348: 37.37
+	Hs
		822136 KC1A_HUMAN (1-337): 1.03e-115: 340: 100.00		FA83C_HUMAN (24-280): 7.36e-105: 346: 41.13