HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0051028 - mRNA transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 579 Hs			1 238
+	Hs
		128165 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		128007 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		432970 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		1031481 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Xl
		251139 IF23A_XENLA (1-579): 1.82e-136: 411: 77.44		EPABA_XENLA (1-95): 1.55e-18: 85.9: 24.00
+	Hs
		516722 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Mm
		888818 PCBP1_MOUSE (277-508): 3.85e-32: 129: 24.14		SRSF7_MOUSE (8-238): 3.54e-29: 112: 97.40
+	Hs
		853900 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		432728 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Mm
		888801 PCBP1_MOUSE (277-508): 3.85e-32: 129: 24.14		SRSF3_MOUSE (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		951974 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		853901 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		951975 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		516530 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		1031417 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		516531 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		963559 FUBP1_HUMAN (353-559): 5.1e-29: 123: 23.22		TIAR_HUMAN (5-97): 6.64e-16: 77.8: 25.51
+	Hs
		433017 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		516769 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Mm
		1130843 IF2B2_MOUSE (79-477): 2.08e-20: 97: 15.76		RBM4_MOUSE (12-89): 2.3e-14: 73.3: 33.33