Protein: PSB3
Proteasome subunit beta type-3 (Macropain subunit PUP3) (Multicatalytic endopeptidase complex subunit PUP3) (Proteasome component PUP3)

Gene: PSB3, PUP3
Organism: Saccharomyces cerevisiae S288C
Interactions: 61
UniProt ID: P25451

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019774 - proteasome core complex, beta-subunit complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

645128

PSB4
Proteasome subunit beta type-4

14

20

Small-scale

0.979

High

675229

PSB5
Proteasome subunit beta type-5

8

20

Small-scale

0.965

High

661457

PSA2
Proteasome subunit alpha type-2

7

20

High-throughput

0.960

High

668365

PSB2
Proteasome subunit beta type-2

7

20

Small-scale

0.956

High

636630

PSA1
Proteasome subunit alpha type-1

4

20

High-throughput

0.896

High

675242

UMP1
Proteasome maturation factor UMP1

4

2

Small-scale

0.881

High

675250

PSA4
Proteasome subunit alpha type-4

3

20

High-throughput

0.855

High

636545

PSA7
Probable proteasome subunit alpha type-7

3

20

High-throughput

0.847

High

661375

PSA3
Proteasome subunit alpha type-3

3

20

High-throughput

0.839

High

675243

PSB1
Proteasome subunit beta type-1

3

20

Small-scale

0.839

High

675230

PSB7
Proteasome subunit beta type-7

3

20

Small-scale

0.830

High

662019

PSB6
Proteasome subunit beta type-6

2

20

High-throughput

0.754

High

675235

PRS6A
26S proteasome regulatory subunit 6A

2

20

High-throughput

0.754

High

675268

RPN5
26S proteasome regulatory subunit RPN5

2

20

Small-scale

0.754

High

675254

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

10

20

Small-scale

0.747

High

675253

BLM10
Proteasome activator BLM10

2

10

Small-scale

0.727

High

675226

FUB1
Silencing boundary-establishment protein FUB1

2

2

High-throughput

0.694

High

675246

RPN10
26S proteasome regulatory subunit RPN10

3

11

High-throughput

0.662

High

675225

PSB3
Proteasome subunit beta type-3

1

19

High-throughput

0.618

High

675232

PSA5
Proteasome subunit alpha type-5

1

20

High-throughput

0.618

High

675236

PRS6B
26S proteasome regulatory subunit 6B homolog

1

20

High-throughput

0.618

High

675237

PRS7
26S proteasome regulatory subunit 7 homolog

1

20

High-throughput

0.618

High

675249

PSA6
Proteasome subunit alpha type-6

1

20

High-throughput

0.618

High

675251

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

675258

PRS8
26S proteasome regulatory subunit 8 homolog

1

20

High-throughput

0.618

High

675270

RPN6
26S proteasome regulatory subunit RPN6

1

20

High-throughput

0.618

High

675263

POC1
Proteasome chaperone 1

1

2

High-throughput

0.553

High

660833

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

2

High-throughput

0.515

High

675256

CDC14
Tyrosine-protein phosphatase CDC14

1

4

High-throughput

0.481

High

314848

SEM1
26S proteasome complex subunit SEM1

1

1

High-throughput

0.479

High

578922

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

670384

SIS1
Protein SIS1

1

4

High-throughput

0.479

High

675228

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

675233

RPN12
26S proteasome regulatory subunit RPN12

1

7

High-throughput

0.479

High

675234

RPN2
26S proteasome regulatory subunit RPN2

1

20

High-throughput

0.479

High

675239

CENPA
Histone H3-like centromeric protein CSE4

1

2

High-throughput

0.479

High

675240

POC2
Proteasome assembly chaperone 2

1

2

High-throughput

0.479

High

675244

ECM29
Proteasome component ECM29

1

13

High-throughput

0.479

High

675245

RPN1
26S proteasome regulatory subunit RPN1

1

20

High-throughput

0.479

High

675247

RPN3
26S proteasome regulatory subunit RPN3

1

9

High-throughput

0.479

High

675255

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

13

High-throughput

0.479

High

675257

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

6

Small-scale

0.479

High

675259

TOM1
E3 ubiquitin-protein ligase TOM1

1

11

High-throughput

0.479

High

675261

RPN9
26S proteasome regulatory subunit RPN9

1

14

High-throughput

0.479

High

675266

RPN8
26S proteasome regulatory subunit RPN8

1

20

High-throughput

0.479

High

675267

PSH1
RING finger protein PSH1

1

6

High-throughput

0.479

High

150265

RPN13
26S proteasome regulatory subunit RPN13

1

0

High-throughput

0.458

High

511543

RL44B
Large ribosomal subunit protein eL42B

1

0

High-throughput

0.458

High

584435

IDI1
Isopentenyl-diphosphate delta-isomerase

1

0

High-throughput

0.458

High

675231

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

675238

SPC29
Spindle pole component 29

1

0

High-throughput

0.458

High

675260

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

675248

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

675227

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

675252

MLP2
Protein MLP2

1

1

High-throughput

0.437

High

675262

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.279

Low

675241

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.249

Low

675264

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low

675265

EFM7
Protein N-terminal and lysine N-methyltransferase EFM7

1

0

High-throughput

0.249

Low

675269

UTP23
rRNA-processing protein UTP23

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025