HitPredict

Interactor 1: LHX2 (P50458)
LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2)
Gene: LHX2

Interactor 2: EHMT2 (Q96KQ7)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)
Gene: EHMT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	GO:0000785 - chromatin GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 1210
+	Hs
		822665 LHX1_HUMAN (53-404): 1.01e-49: 174: 26.63		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1296441 LHX6_HUMAN (111-368): 2.79e-21: 96.4: 21.32		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		839827 LHX2_HUMAN (1-406): 2.55e-97: 298: 100.00		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		1281166 LHX4_HUMAN (34-107): 2.07e-11: 67.1: 23.68		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		1296429 LHX3_HUMAN (27-113): 1e-09: 61.7: 22.47		EHMT2_HUMAN (21-1210): 0: 909: 100.00
+	Hs
		822681 LHX1_HUMAN (53-404): 1.01e-49: 174: 26.63		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		1281184 LHX4_HUMAN (34-107): 2.07e-11: 67.1: 23.68		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		1334137 LHX3_HUMAN (27-113): 1e-09: 61.7: 22.47		EHMT1_HUMAN (1-1209): 0: 685: 45.63
+	Hs
		203710 LHX8_HUMAN (115-394): 4.48e-35: 134: 23.84		SUV91_HUMAN (861-1179): 1.67e-78: 266: 30.51
+	Hs
		257707 LHX9_HUMAN (1-406): 3.73e-76: 243: 61.58		ANR17_HUMAN (51-672): 1.96e-25: 117: 7.86
+	Hs
		150542 ABLM1_HUMAN (42-352): 2.87e-27: 116: 14.47		DAPK1_HUMAN (672-1049): 2.27e-52: 203: 17.06
+	Hs
		823450 PAXI_HUMAN (15-111): 1.09e-14: 77.9: 19.59		ANR52_HUMAN (394-767): 4.88e-48: 189: 12.40
+	Hs
		823441 PAXI_HUMAN (15-111): 1.09e-14: 77.9: 19.59		ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09
+	Hs
		1219793 LMO3_HUMAN (53-108): 5.21e-10: 59.2: 28.07		ANKH1_HUMAN (673-1018): 7.75e-44: 177: 19.09
+	Hs
		638561 RBTN1_HUMAN (33-171): 5.63e-40: 141: 41.84		ASPP1_HUMAN (755-871): 8.39e-14: 78.5: 20.00
+	Hs
		1251433 LMO3_HUMAN (53-108): 5.21e-10: 59.2: 28.07		ASPP1_HUMAN (755-871): 8.39e-14: 78.5: 20.00