HitPredict

Interactor 1: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1647 Hs			1 538
+	Hs
		853716 Q9HBD4_HUMAN (1-1647): 0: 1096: 97.38		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		131405 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91
+	Hs
		846901 SMCA4_HUMAN (1-1647): 0: 1105: 100.00		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Hs
		846726 SMCA2_HUMAN (1-1647): 0: 980: 71.69		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		846725 SMCA2_HUMAN (1-1647): 0: 980: 71.69		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Hs
		229344 SMCA5_HUMAN (626-1631): 0: 835: 27.41		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		658643 SMCA1_HUMAN (639-1619): 0: 832: 28.82		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		238679 CHD4_HUMAN (482-1630): 0: 722: 23.79		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Hs
		853602 CHD4_HUMAN (482-1630): 0: 722: 23.79		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		134899 CHD4_HUMAN (482-1630): 0: 722: 23.79		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Hs
		238743 CHD8_HUMAN (13-1523): 0: 711: 21.11		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Mm
		1000155 CHD8_MOUSE (18-1527): 0: 718: 20.36		IMA5_MOUSE (1-538): 1.75e-154: 453: 97.77
+	Hs
		168636 CHD4_HUMAN (482-1630): 0: 722: 23.79		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Sc
		744898 ISW1_YEAST (550-1646): 0: 745: 25.77		IMA1_YEAST (2-538): 8.07e-143: 424: 49.26
+	Hs
		134969 CHD8_HUMAN (13-1523): 0: 711: 21.11		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Mm
		192636 CHD8_MOUSE (18-1527): 0: 718: 20.36		IMA4_MOUSE (3-538): 1.37e-152: 448: 46.10
+	Hs
		853286 CHD4_HUMAN (482-1630): 0: 722: 23.79		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Hs
		168673 CHD8_HUMAN (13-1523): 0: 711: 21.11		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Mm
		853539 CHD8_MOUSE (18-1527): 0: 718: 20.36		IMA1_MOUSE (3-538): 2.83e-147: 435: 44.18
+	Dm
		853771 ISWI_DROME (692-1647): 0: 771: 28.17		IMA_DROME (3-538): 3.76e-121: 367: 43.60