Interactor 1: GDIR1 (P52565)
Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha)
Gene: ARHGDIA

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 17353931, 10673424, 9490022, 11368848, 19961560, 27173435, 31980649, 11513578, 11513579, 31871319, 35271311, 21900206, 22393046, 17245428, 22157745, unassigned2173
Identification Methods affinity chromatography technology, x-ray crystallography, biochemical, two hybrid, pull down, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~Rho_GDI
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0016020 - membrane
GO:0070062 - extracellular exosome
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 204
Hs

1 192
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Last updated: 15 Jul 2024