HitPredict

Interactor 1: C1C3I0 (C1C3I0)
Eukaryotic translation initiation factor 4E homologous protein, isoform C (MIP06235p)
Gene: eIF4EHP

Interactor 2: DDX6 (P23128)
ATP-dependent RNA helicase me31b (EC 3.6.4.13) (Maternal expression at 31B)
Gene: me31B

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31114929, 35020877
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0017148 - negative regulation of translation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 186 Dm			1 459
+	Dm
		820456 IF4E_DROME (17-164): 7.92e-63: 196: 26.97		DDX3_DROME (7-430): 5.88e-148: 442: 26.61
+	Dm
		612586 IF4E_DROME (17-164): 7.92e-63: 196: 26.97		DDX6_DROME (1-459): 1.55e-145: 425: 100.00
+	Dm
		612744 Q9VSG1_DROME (45-164): 1.59e-58: 184: 33.33		DDX6_DROME (1-459): 1.55e-145: 425: 100.00
+	Sc
		424865 IF4E_YEAST (1-165): 1.37e-61: 191: 25.00		DHH1_YEAST (31-438): 1.27e-131: 391: 68.38
+	Hs
		133842 IF4E_HUMAN (30-164): 2.82e-61: 191: 29.29		DDX3X_HUMAN (4-434): 1.59e-128: 388: 25.50
+	Sc
		415856 IF4E_YEAST (1-165): 1.37e-61: 191: 25.00		DED1_YEAST (8-459): 3.38e-128: 385: 25.53
+	Hs
		416933 IF4E_HUMAN (30-164): 2.82e-61: 191: 29.29		DDX6_HUMAN (2-434): 3.79e-127: 379: 70.28
+	Sc
		424800 IF4E_YEAST (1-165): 1.37e-61: 191: 25.00		IF4A_YEAST (59-425): 1.32e-79: 254: 39.57