HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: PELP1 (Q8IZL8)
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3)
Gene: PELP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23667531
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 1130
+	Hs
		1316591 TF7L2_HUMAN (14-255): 1.15e-34: 134: 19.75		PELP1_HUMAN (1-1130): 0: 784: 100.00
+	Hs
		872830 SOX2_HUMAN (1-317): 7.52e-76: 236: 100.00		CHD7_HUMAN (484-1110): 2.39e-32: 139: 13.45
+	Hs
		872258 SOX2_HUMAN (1-317): 7.52e-76: 236: 100.00		EP300_HUMAN (697-1119): 6.36e-12: 72.7: 11.21
+	Hs
		872662 SOX2_HUMAN (1-317): 7.52e-76: 236: 100.00		MINT_HUMAN (731-1119): 5.58e-11: 69.6: 12.21
+	Hs
		872546 SOX2_HUMAN (1-317): 7.52e-76: 236: 100.00		KMT2C_HUMAN (677-1122): 3.49e-09: 63.5: 9.51
+	Hs
		776139 SOX5_HUMAN (2-127): 7.95e-43: 158: 41.27		CHD7_HUMAN (484-1110): 2.39e-32: 139: 13.45
+	Mm
		59403 Q60I23_MOUSE (1-317): 2.37e-73: 230: 96.24		CHD7_MOUSE (495-998): 1.66e-09: 64.7: 8.51
+	Mm
		873026 SOX2_MOUSE (1-317): 2.25e-70: 223: 94.67		CHAP1_MOUSE (554-1041): 5.97e-10: 65.8: 12.90
+	Hs
		873124 SOX9_HUMAN (28-260): 6.26e-37: 139: 27.57		CHD7_HUMAN (484-1110): 2.39e-32: 139: 13.45
+	Hs
		1434979 SOX17_HUMAN (7-260): 2.4e-33: 128: 27.80		CHD7_HUMAN (484-1110): 2.39e-32: 139: 13.45
+	Hs
		873111 SOX9_HUMAN (28-260): 6.26e-37: 139: 27.57		CBP_HUMAN (631-1010): 2.06e-28: 126: 16.87
+	Rn
		98827 SOX9_RAT (28-260): 9.78e-39: 144: 27.98		F1M9G7_RAT (631-1010): 7.55e-27: 121: 17.73
+	Hs
		1368470 SOX7_HUMAN (23-299): 4e-33: 127: 27.03		CBP_HUMAN (631-1010): 2.06e-28: 126: 16.87
+	Hs
		873076 SOX9_HUMAN (28-260): 6.26e-37: 139: 27.57		EP300_HUMAN (697-1119): 6.36e-12: 72.7: 11.21
+	Hs
		1067746 TF7L2_HUMAN (14-255): 1.15e-34: 134: 19.75		EP300_HUMAN (697-1119): 6.36e-12: 72.7: 11.21
+	Hs
		873102 SOX9_HUMAN (28-260): 6.26e-37: 139: 27.57		KMT2C_HUMAN (677-1122): 3.49e-09: 63.5: 9.51
+	Hs
		1067662 SOX7_HUMAN (23-299): 4e-33: 127: 27.03		EP300_HUMAN (697-1119): 6.36e-12: 72.7: 11.21
+	Hs
		1129757 TF7L2_HUMAN (14-255): 1.15e-34: 134: 19.75		MDC1_HUMAN (516-1125): 4.8e-09: 63.1: 10.91
+	Hs
		1338275 SOX17_HUMAN (7-260): 2.4e-33: 128: 27.80		KMT2C_HUMAN (677-1122): 3.49e-09: 63.5: 9.51
+	Hs
		1338269 SOX7_HUMAN (23-299): 4e-33: 127: 27.03		KMT2C_HUMAN (677-1122): 3.49e-09: 63.5: 9.51