HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: DCAF5 (Q80T85)
DDB1- and CUL4-associated factor 5 (WD repeat-containing protein 22)
Gene: DCAF5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30442713
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 319 Mm			1 946
+	Hs
		872635 SOX2_HUMAN (1-319): 9.05e-67: 213: 94.67		DCAF5_HUMAN (1-946): 0: 718: 89.19
+	Rn
		93012 SOX10_RAT (34-192): 2.19e-47: 167: 40.88		D3ZQU4_RAT (171-519): 1.19e-55: 205: 12.05
+	Mm
		1222141 Q60I23_MOUSE (1-319): 5.92e-68: 216: 98.43		TBL1R_MOUSE (228-549): 9.44e-36: 144: 9.77
+	Hs
		872721 SOX2_HUMAN (1-319): 9.05e-67: 213: 94.67		TBL1R_HUMAN (228-549): 1.28e-35: 144: 9.77
+	Hs
		222472 SSRP1_HUMAN (21-205): 1.02e-33: 132: 15.14		PLRG1_HUMAN (49-386): 3.28e-61: 218: 20.52
+	Hs
		1065316 SSRP1_HUMAN (21-205): 1.02e-33: 132: 15.14		GEMI5_HUMAN (40-930): 8.15e-55: 209: 12.13
+	Hs
		872181 SOX2_HUMAN (1-319): 9.05e-67: 213: 94.67		RACK1_HUMAN (2-176): 7.33e-31: 126: 14.10
+	Hs
		873117 SOX9_HUMAN (27-262): 9.99e-39: 144: 27.24		FBXW7_HUMAN (171-488): 4.28e-42: 166: 12.73
+	Hs
		1380178 HM20A_HUMAN (1-278): 2.4e-37: 138: 13.17		FBXW7_HUMAN (171-488): 4.28e-42: 166: 12.73
+	Hs
		1380183 TF7L2_HUMAN (46-269): 1e-35: 137: 19.11		FBXW7_HUMAN (171-488): 4.28e-42: 166: 12.73
+	Hs
		1065344 SSRP1_HUMAN (21-205): 1.02e-33: 132: 15.14		FBXW7_HUMAN (171-488): 4.28e-42: 166: 12.73
+	Hs
		992919 CIC_HUMAN (10-274): 2.9e-43: 160: 23.83		RACK1_HUMAN (2-176): 7.33e-31: 126: 14.10
+	Hs
		872148 SOX2_HUMAN (1-319): 9.05e-67: 213: 94.67		WDR5_HUMAN (1-84): 1.99e-10: 65.3: 15.12
+	Mm
		872998 SOX2_MOUSE (1-319): 1.16e-66: 213: 100.00		HIRA_MOUSE (5-177): 6.66e-10: 65.3: 14.56
+	Hs
		1065414 SSRP1_HUMAN (21-205): 1.02e-33: 132: 15.14		TBL1R_HUMAN (228-549): 1.28e-35: 144: 9.77
+	Hs
		965173 CIC_HUMAN (10-274): 2.9e-43: 160: 23.83		WDR5_HUMAN (1-84): 1.99e-10: 65.3: 15.12
+	Hs
		1387578 HM20A_HUMAN (1-278): 2.4e-37: 138: 13.17		SNR40_HUMAN (363-557): 1.37e-11: 69.1: 12.22
+	Hs
		926689 TF7L2_HUMAN (46-269): 1e-35: 137: 19.11		HIRA_HUMAN (5-177): 2.51e-10: 66.8: 14.56
+	Hs
		1065355 SSRP1_HUMAN (21-205): 1.02e-33: 132: 15.14		SNR40_HUMAN (363-557): 1.37e-11: 69.1: 12.22
+	Hs
		964889 SSRP1_HUMAN (21-205): 1.02e-33: 132: 15.14		WDR5_HUMAN (1-84): 1.99e-10: 65.3: 15.12