HitPredict

Interactor 1: MRCKA (O54874)
Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)
Gene: Cdc42bpa

Interactor 2: MRCKA (O54874)
Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)
Gene: Cdc42bpa

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 18854160, 11283256, 11340065
Identification Methods protein kinase assay, molecular sieving
Interaction Type phosphorylation reaction, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~Pkinase, DMPK_coil~DMPK_coil, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0000287 - magnesium ion binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
and 13 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1732
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Last updated: 15 Jul 2024