HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: Q9DCC5 (Q9DCC5)
Cbx3 protein (Chromobox 3)
Gene: Cbx3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.50	0.512

Property	Details
Experiments	31077711
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 319 Mm			1 183
+	Mm
		872999 SOX2_MOUSE (1-319): 1.16e-66: 213: 100.00		CBX5_MOUSE (11-182): 1.22e-55: 175: 59.89
+	Mm
		872974 SOX2_MOUSE (1-319): 1.16e-66: 213: 100.00		CBX1_MOUSE (36-180): 1.03e-53: 170: 71.33
+	Hs
		1097507 CIC_HUMAN (10-274): 2.9e-43: 160: 23.83		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1097451 BBX_HUMAN (31-253): 2.86e-35: 137: 19.30		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1097580 TF7L2_HUMAN (46-269): 1e-35: 137: 19.11		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		1065170 SSRP1_HUMAN (21-205): 1.02e-33: 132: 15.14		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		355511 NSD2_HUMAN (1-288): 6.06e-30: 122: 12.54		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		853383 CIC_HUMAN (10-274): 2.9e-43: 160: 23.83		CBX5_HUMAN (11-182): 1.63e-55: 175: 59.89
+	Hs
		129679 SOX2_HUMAN (1-319): 9.05e-67: 213: 94.67		CBX4_HUMAN (21-121): 4.97e-27: 108: 29.52
+	Hs
		872333 SOX2_HUMAN (1-319): 9.05e-67: 213: 94.67		CBX2_HUMAN (20-117): 6e-25: 102: 27.00
+	Hs
		604651 UBF1_HUMAN (17-131): 3.8e-19: 90.1: 22.61		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Dm
		120148 M9PCG2_DROME (13-165): 2.54e-34: 133: 52.29		Q9VCU6_DROME (25-170): 2.08e-46: 153: 39.46
+	Dm
		1470755 Q9VUD3_DROME (3-215): 1.1e-27: 114: 39.91		Q9VCU6_DROME (25-170): 2.08e-46: 153: 39.46
+	Hs
		776131 SOX5_HUMAN (17-129): 1.87e-39: 149: 40.71		CBX8_HUMAN (21-116): 2.35e-26: 104: 32.00
+	Hs
		338978 TF7L2_HUMAN (46-269): 1e-35: 137: 19.11		CBX6_HUMAN (21-124): 3.32e-27: 107: 27.78
+	Hs
		1065197 SSRP1_HUMAN (21-205): 1.02e-33: 132: 15.14		CBX2_HUMAN (20-117): 6e-25: 102: 27.00