HitPredict

Interactor 1: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Interactor 2: CCNQ (Q8N1B3)
Cyclin-Q (CDK10-activating cyclin) (Cyclin-M) (Cyclin-related protein FAM58A)
Gene: CCNQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cyclin_N~Pkinase
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 248
+	Hs
		252236 CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00		CCNT2_HUMAN (6-242): 5.29e-72: 234: 21.76
+	Hs
		251544 CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00		CCNT1_HUMAN (6-243): 2.99e-62: 209: 20.00
+	Hs
		629086 CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00		CCNA2_HUMAN (1-248): 1.39e-64: 208: 15.26
+	At
		1426030 CDKC1_ARATH (6-367): 5.88e-137: 401: 42.97		CCT15_ARATH (6-245): 9.84e-72: 231: 25.00
+	At
		1355591 CDKC2_ARATH (6-367): 2.08e-136: 400: 43.24		CCT15_ARATH (6-245): 9.84e-72: 231: 25.00
+	Hs
		296969 CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00		CCNK_HUMAN (8-247): 8.02e-62: 205: 24.38
+	Mm
		1408622 CDK9_MOUSE (1-372): 1.39e-147: 423: 98.66		CCNT1_MOUSE (6-243): 1.57e-61: 207: 20.00
+	Mm
		1274590 CDK9_MOUSE (1-372): 1.39e-147: 423: 98.66		CCNT2_MOUSE (6-243): 3.69e-61: 206: 20.42
+	At
		1300177 CDKC1_ARATH (6-367): 5.88e-137: 401: 42.97		CCT14_ARATH (6-245): 5.6e-71: 228: 24.59
+	At
		1300176 CDKC2_ARATH (6-367): 2.08e-136: 400: 43.24		CCT14_ARATH (6-245): 5.6e-71: 228: 24.59
+	At
		1319510 CDKC1_ARATH (6-367): 5.88e-137: 401: 42.97		CCT13_ARATH (5-244): 6.23e-71: 221: 20.90
+	At
		1319509 CDKC2_ARATH (6-367): 2.08e-136: 400: 43.24		CCT13_ARATH (5-244): 6.23e-71: 221: 20.90
+	Hs
		667764 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		CCNA1_HUMAN (1-248): 1.45e-69: 222: 16.87
+	Hs
		573751 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		CCNB1_HUMAN (1-242): 2.33e-66: 213: 11.57
+	Hs
		629061 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		CCNA2_HUMAN (1-248): 1.39e-64: 208: 15.26
+	Hs
		325466 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		CCNB2_HUMAN (1-243): 4.01e-63: 204: 11.93
+	Hs
		297037 CDK12_HUMAN (16-371): 2.05e-123: 390: 42.54		CCNK_HUMAN (8-247): 8.02e-62: 205: 24.38
+	At
		1355725 CDKC1_ARATH (6-367): 5.88e-137: 401: 42.97		CCH11_ARATH (5-205): 7.4e-23: 97: 18.93
+	At
		1355590 CDKC2_ARATH (6-367): 2.08e-136: 400: 43.24		CCH11_ARATH (5-205): 7.4e-23: 97: 18.93
+	Hs
		667665 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		CCNH_HUMAN (43-209): 1.32e-22: 95.9: 19.16