HitPredict

Interactor 1: SMCA4 (P51532)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 (SMARCA4) (EC 3.6.4.-) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (Transcription activator BRG1)
Gene: SMARCA4

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 28514442, 29374058, 24981860, 33961781, 18809673, 20305087, 9584200, 30962207, 8895581, 11726552, 9845365, 31043422, 35271311, 14559996, 18086889, 20460684, 22573825, unassigned3799, 10078207, 12368262 and 2 others

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Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Myb_DNA-binding~QLQ
Common GO terms GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0003713 - transcription coactivator activity
GO:0005654 - nucleoplasm
GO:0006337 - nucleosome disassembly
and 21 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 11Aug2025