HitPredict

Interactor 1: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Interactor 2: CSR2B (Q9H8E8)
Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP) (Lysine acetyltransferase 14)
Gene: KAT14

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.950

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 27705803, 24981860, 33961781, 21531708
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Acetyltransf_1~WD40
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II and 6 others more... GO:0045995 - regulation of embryonic development GO:0051302 - regulation of cell division GO:0051726 - regulation of cell cycle GO:0072686 - mitotic spindle GO:0090043 - regulation of tubulin deacetylation GO:0140672 - ATAC complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	334
Hs

1	782

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024