HitPredict

Interactor 1: D3YT54 (D3YT54)
Rho-GAP domain-containing protein
Gene: srgp-1

Interactor 2: RAC1 (Q03206)
Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1)
Gene: ced-10

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	21170032
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 611 Ce			1 191
+	Ce
		92547 D3YT54_CAEEL (1-611): 1.62e-130: 397: 100.00		CDC42_CAEEL (1-191): 2.49e-76: 228: 70.68
+	Hs
		212765 SRGP3_HUMAN (28-594): 6.72e-94: 313: 24.44		RAC1_HUMAN (1-191): 2.34e-81: 241: 82.81
+	Hs
		988485 SRGP1_HUMAN (29-601): 1.06e-92: 310: 24.58		RAC1_HUMAN (1-191): 2.34e-81: 241: 82.81
+	Hs
		601322 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RHOQ_HUMAN (4-187): 2.02e-82: 244: 60.87
+	Hs
		988431 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RAC1_HUMAN (1-191): 2.34e-81: 241: 82.81
+	Hs
		1015505 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RHOG_HUMAN (1-191): 3.15e-79: 235: 66.49
+	Hs
		581097 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RAC2_HUMAN (1-191): 4.75e-78: 233: 79.17
+	Hs
		955270 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		CDC42_HUMAN (1-191): 1.97e-77: 231: 65.97
+	Hs
		962118 RHG29_HUMAN (2-596): 3.87e-92: 310: 14.49		RHOA_HUMAN (5-191): 8.96e-76: 227: 56.15
+	Hs
		962215 SRGP1_HUMAN (29-601): 1.06e-92: 310: 24.58		RHOA_HUMAN (5-191): 8.96e-76: 227: 56.15
+	Hs
		988442 RHG17_HUMAN (52-611): 4.68e-89: 296: 16.46		RAC1_HUMAN (1-191): 2.34e-81: 241: 82.81
+	Hs
		953496 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RAC3_HUMAN (1-177): 9.67e-76: 227: 84.75
+	Hs
		962142 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RHOA_HUMAN (5-191): 8.96e-76: 227: 56.15
+	Hs
		1213085 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RHOJ_HUMAN (2-189): 3.07e-75: 226: 56.38
+	Hs
		955287 RHG17_HUMAN (52-611): 4.68e-89: 296: 16.46		CDC42_HUMAN (1-191): 1.97e-77: 231: 65.97
+	Mm
		953811 SRGP1_MOUSE (29-601): 2.46e-87: 294: 23.96		CDC42_MOUSE (1-191): 1.97e-77: 231: 65.97
+	Mm
		1362439 SRGP1_MOUSE (29-601): 2.46e-87: 294: 23.96		RHOA_MOUSE (5-191): 3.5e-76: 228: 55.62
+	Mm
		953807 RHG33_MOUSE (4-597): 3.74e-84: 288: 15.03		CDC42_MOUSE (1-191): 1.97e-77: 231: 65.97
+	Hs
		67609 RHG32_HUMAN (15-596): 1.13e-81: 283: 17.32		RAC2_HUMAN (1-191): 4.75e-78: 233: 79.17
+	Hs
		67604 RHG32_HUMAN (15-596): 1.13e-81: 283: 17.32		RHOC_HUMAN (5-191): 9.77e-74: 221: 54.55