HitPredict

Interactor 1: D3YT54 (D3YT54)
Rho-GAP domain-containing protein
Gene: srgp-1

Interactor 2: CDC42 (Q05062)
Cell division control protein 42 homolog (CDC42Ce)
Gene: cdc-42

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24632947
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005737 - cytoplasm GO:0005938 - cell cortex GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 611 Ce			1 191
+	Ce
		92546 D3YT54_CAEEL (1-611): 1.62e-130: 397: 100.00		RAC1_CAEEL (1-191): 2.09e-81: 241: 70.68
+	Hs
		1213085 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RHOJ_HUMAN (2-189): 5.55e-84: 248: 63.30
+	Hs
		212765 SRGP3_HUMAN (28-594): 6.72e-94: 313: 24.44		RAC1_HUMAN (1-191): 1.12e-79: 236: 69.11
+	Hs
		988485 SRGP1_HUMAN (29-601): 1.06e-92: 310: 24.58		RAC1_HUMAN (1-191): 1.12e-79: 236: 69.11
+	Hs
		988431 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RAC1_HUMAN (1-191): 1.12e-79: 236: 69.11
+	Hs
		962118 RHG29_HUMAN (2-596): 3.87e-92: 310: 14.49		RHOA_HUMAN (5-191): 4.21e-76: 228: 51.87
+	Hs
		962215 SRGP1_HUMAN (29-601): 1.06e-92: 310: 24.58		RHOA_HUMAN (5-191): 4.21e-76: 228: 51.87
+	Hs
		1015505 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RHOG_HUMAN (1-191): 2.37e-77: 231: 58.12
+	Hs
		955270 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		CDC42_HUMAN (1-191): 3.92e-77: 230: 86.39
+	Mm
		1282996 RHG33_MOUSE (4-597): 3.74e-84: 288: 15.03		RHOJ_MOUSE (2-179): 8.09e-83: 246: 64.61
+	Hs
		581097 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RAC2_HUMAN (1-191): 2.38e-76: 228: 67.71
+	Hs
		962142 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RHOA_HUMAN (5-191): 4.21e-76: 228: 51.87
+	Hs
		988442 RHG17_HUMAN (52-611): 4.68e-89: 296: 16.46		RAC1_HUMAN (1-191): 1.12e-79: 236: 69.11
+	Hs
		953496 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RAC3_HUMAN (1-177): 1.26e-74: 224: 70.62
+	Hs
		955287 RHG17_HUMAN (52-611): 4.68e-89: 296: 16.46		CDC42_HUMAN (1-191): 3.92e-77: 230: 86.39
+	Hs
		601322 RHG21_HUMAN (1-595): 7.23e-90: 306: 21.90		RHOQ_HUMAN (4-191): 1.88e-72: 219: 64.62
+	Mm
		953811 SRGP1_MOUSE (29-601): 2.46e-87: 294: 23.96		CDC42_MOUSE (1-191): 3.92e-77: 230: 86.39
+	Mm
		1362439 SRGP1_MOUSE (29-601): 2.46e-87: 294: 23.96		RHOA_MOUSE (5-191): 1.57e-76: 229: 52.41
+	Mm
		953807 RHG33_MOUSE (4-597): 3.74e-84: 288: 15.03		CDC42_MOUSE (1-191): 3.92e-77: 230: 86.39
+	Hs
		67604 RHG32_HUMAN (15-596): 1.13e-81: 283: 17.32		RHOC_HUMAN (5-191): 3.27e-74: 223: 50.80