HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: PHC1 (P78364)
Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1)
Gene: PHC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~SAM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 1004
+	Hs
		586680 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		PHC1_HUMAN (1-1004): 1.29e-86: 302: 100.00
+	Hs
		934545 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		SMBT1_HUMAN (826-1002): 3.82e-35: 146: 28.57
+	Hs
		554284 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		MUC1_HUMAN (5-886): 1.17e-47: 187: 9.75
+	Hs
		297825 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		K0754_HUMAN (22-520): 1.85e-24: 113: 8.77
+	Hs
		587048 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		SMBT1_HUMAN (826-1002): 3.82e-35: 146: 28.57
+	Hs
		625646 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		SCML2_HUMAN (590-1003): 5.22e-31: 132: 16.14
+	At
		1105568 KSG7_ARATH (39-375): 4.65e-118: 349: 27.95		IF4G_ARATH (208-731): 1.77e-30: 132: 14.21
+	Hs
		92118 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		NACAM_HUMAN (439-955): 3.87e-09: 63.1: 10.06
+	Hs
		934291 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		PHC2_HUMAN (22-663): 5.23e-09: 62.3: 11.37
+	Hs
		934361 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		CBP_HUMAN (236-907): 8.37e-09: 61.9: 8.86
+	Hs
		625532 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		CBP_HUMAN (236-907): 8.37e-09: 61.9: 8.86
+	Hs
		836087 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		SCML1_HUMAN (863-1003): 2.3e-15: 80.5: 27.10
+	Hs
		586864 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		PHC3_HUMAN (180-907): 1.62e-09: 64.2: 7.91
+	Hs
		586843 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		PHC2_HUMAN (22-663): 5.23e-09: 62.3: 11.37
+	Hs
		586895 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		CBP_HUMAN (236-907): 8.37e-09: 61.9: 8.86