HitPredict

Interactor 1: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: PKHA1 (Q9HB21)
Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1)
Gene: PLEKHA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FHA~PH
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1824 Hs			1 404
+	Hs
		936359 AFAD_HUMAN (1-1824): 0: 1266: 100.00		PKHA7_HUMAN (105-397): 4.38e-34: 136: 17.24
+	Hs
		936451 AFAD_HUMAN (1-1824): 0: 1266: 100.00		PKHA5_HUMAN (130-342): 1.6e-33: 135: 20.55
+	Hs
		1090185 PTN13_HUMAN (978-1091): 1.19e-17: 92.2: 35.83		PKHA1_HUMAN (1-404): 4.74e-120: 356: 100.00
+	Hs
		1152420 DLG2_HUMAN (936-1152): 2.01e-33: 142: 23.77		PKHA2_HUMAN (1-404): 4.23e-99: 303: 43.52
+	Hs
		299794 MPDZ_HUMAN (971-1166): 2.32e-13: 77.9: 21.43		PKHA1_HUMAN (1-404): 4.74e-120: 356: 100.00
+	Hs
		1368721 DLG3_HUMAN (1009-1248): 4.09e-22: 106: 18.50		PKHA2_HUMAN (1-404): 4.23e-99: 303: 43.52
+	Ce
		661897 UN104_CAEEL (183-614): 5.6e-71: 266: 16.56		UN104_CAEEL (15-315): 2.31e-32: 131: 16.07
+	Hs
		1090184 PTN13_HUMAN (978-1091): 1.19e-17: 92.2: 35.83		PKHA2_HUMAN (1-404): 4.23e-99: 303: 43.52
+	Hs
		1140557 KIF14_HUMAN (175-624): 1.61e-57: 222: 18.72		AFAP1_HUMAN (6-399): 3.95e-47: 173: 13.70
+	Hs
		299793 MPDZ_HUMAN (971-1166): 2.32e-13: 77.9: 21.43		PKHA2_HUMAN (1-404): 4.23e-99: 303: 43.52
+	Hs
		1234971 KI13B_HUMAN (184-691): 2.15e-62: 238: 13.13		PKHA7_HUMAN (105-397): 4.38e-34: 136: 17.24
+	Hs
		1437668 KI13B_HUMAN (184-691): 2.15e-62: 238: 13.13		PKHA5_HUMAN (130-342): 1.6e-33: 135: 20.55
+	Hs
		1141100 KIF14_HUMAN (175-624): 1.61e-57: 222: 18.72		FARP1_HUMAN (19-303): 3.66e-38: 148: 12.24
+	Hs
		225478 KIF14_HUMAN (175-624): 1.61e-57: 222: 18.72		CYH3_HUMAN (193-289): 5.32e-32: 126: 25.83
+	Hs
		1140318 KIF14_HUMAN (175-624): 1.61e-57: 222: 18.72		CYH1_HUMAN (193-289): 1.24e-30: 123: 25.83
+	Hs
		1140628 KIF14_HUMAN (175-624): 1.61e-57: 222: 18.72		ARAP2_HUMAN (210-301): 1.88e-11: 68.1: 14.74
+	Hs
		1140452 KIF14_HUMAN (175-624): 1.61e-57: 222: 18.72		MPRIP_HUMAN (203-403): 9.94e-11: 65.8: 16.26
+	Mm
		148523 DLG4_MOUSE (952-1591): 2.35e-24: 113: 11.13		CYH3_MOUSE (193-289): 1.43e-33: 131: 26.05
+	Hs
		1327353 MYO5C_HUMAN (1238-1640): 3.78e-09: 64.2: 6.81		AFAP1_HUMAN (6-399): 3.95e-47: 173: 13.70
+	Mm
		989414 DLG4_MOUSE (952-1591): 2.35e-24: 113: 11.13		CYH2_MOUSE (193-290): 4.94e-31: 124: 24.79