Interactor 1: TANK (P70347)
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)
Gene: TANK

Interactor 2: RIPK1 (Q60855)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 31149635, 21419663
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0031625 - ubiquitin protein ligase binding
GO:0032991 - protein-containing complex
GO:0043124 - negative regulation of canonical NF-kappaB signal transduction
GO:0071356 - cellular response to tumor necrosis factor
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 448
Mm

1 656
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024