Interactor 1: CASP6 (P55212)
Caspase-6 (CASP-6) (CSP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18 (Caspase-6 subunit p20); Caspase-6 subunit p11 (Caspase-6 subunit p10)]
Gene: CASP6
Interactor 2: CASP6 (P55212)
Caspase-6 (CASP-6) (CSP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18 (Caspase-6 subunit p20); Caspase-6 subunit p11 (Caspase-6 subunit p10)]
Gene: CASP6
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.968 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, 12232792, 21988832, 8900201, 31515488, unassigned1304, 20890311 |
| Identification Methods | two hybrid, enzymatic study, protease assay, two hybrid array, two hybrid prey pooling approach, validated two hybrid, x-ray crystallography |
| Interaction Type | direct interaction, protein cleavage, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Peptidase_C14~Peptidase_C14 |
| Common GO terms | GO:0002218 - activation of innate immune response GO:0004197 - cysteine-type endopeptidase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 14 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
